Perfusion computed tomography in colorectal cancer: Protocols, clinical applications and emerging trends
文献类型：期刊论文
| 作者 | Wu, GY ; Ghimire, P |
| 刊名 | WORLD JOURNAL OF GASTROENTEROLOGY
 |
| 出版日期 | 2010 |
| 卷号 | 15期号:26页码:3228-3231 |
| 关键词 | Colorectal cancers Perfusion computed tomography Angiogenesis Neovascularization Micrometastases |
| 通讯作者 | Wu, GY (reprint author), Wuhan Univ, Zhongnan Hosp, Dept Magnet Resonance Imaging, 169 E Lake Rd, Wuhan 430071, Hubei Province, Peoples R China. |
| 英文摘要 | Perfusion computed tomography (CT) has emerged as a novel functional imaging technique with gradually increasing importance in the management of colorectal cancer (CRC). By providing the functional tumor microvasculature, it also helps the assessment of therapeutic response of anti-angiogenic drugs as it may reflect tumor angiogenesis. Perfusion CT has been applied in clinical practice to delineate inflammatory or neoplastic lymph nodes irrespective of their size, identify micro-metastases and to predict metastases in advance of their development. It is of increasing significance for preoperative adjuvant therapies and avoidance of unnecessary interventions. Despite controversies regarding the techniques employed, its validity and reproducibility, it can be advantageous in the management of CRCs in which the prognosis is dependent on preoperative staging. With recent advances in the perfusion CT techniques, and incorporation to other modalities like positron emission tomography, perfusion CT will be a novel tool in the overall management of CRCs. This article aims at reviewing the existing clinical applications and recent advances of perfusion CT with a reference to future development in the management of CRCs. (C) 2009 The WJG Press and Baishideng. All rights reserved. |
| 研究领域[WOS] | TUMOR ANGIOGENESIS ; QUANTITATIVE ASSESSMENT ; CONTRAST ENHANCEMENT ; VASCULAR PARAMETERS ; INITIAL-EXPERIENCE ; RECTAL-CANCER ; CT ASSESSMENT ; ONCOLOGY ; EXPRESSION ; CARCINOMA |
| 公开日期 | 2015-07-14 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/2194]  |
| 专题 | 武汉物理与数学研究所_2011年以前论文发表（包括2011年） |
| 推荐引用方式 GB/T 7714 | Wu, GY,Ghimire, P. Perfusion computed tomography in colorectal cancer: Protocols, clinical applications and emerging trends[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2010,15(26):3228-3231. |
| APA | Wu, GY,&Ghimire, P.(2010).Perfusion computed tomography in colorectal cancer: Protocols, clinical applications and emerging trends.WORLD JOURNAL OF GASTROENTEROLOGY,15(26),3228-3231. |
| MLA | Wu, GY,et al."Perfusion computed tomography in colorectal cancer: Protocols, clinical applications and emerging trends".WORLD JOURNAL OF GASTROENTEROLOGY 15.26(2010):3228-3231. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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