Combined action of MK-801 and ceftriaxone impairs the acquisition and reinstatement of morphine-induced conditioned place preference, and delays morphine extinction in rats
文献类型：期刊论文
| 作者 | Fan, Yaodong2,3,5; Niu, Haichen1; Rizak, Joshua D.3; Li, Ling4; Wang, Guimei4; Xu, Liqi4; Ren, He4; Lei, Hao1; Yu, Hualin5 |
| 刊名 | NEUROSCIENCE BULLETIN
 |
| 出版日期 | 2012-10-01 |
| 卷号 | 28期号:5页码:567-576 |
| 关键词 | ceftriaxone conditioned place preference morphine MK-801 glutamate transporter subtype-1 |
| 英文摘要 | It is well established that glutamate and its receptors, particularly the N-methyl-D-aspartate receptor (NMDAR), play a significant role in addiction and that the inhibition of glutamatergic hyperfunction reduces addictive behaviors in experimental animals. Specifically, NMDAR antagonists such as MK-801, and an inducer of the expression of glutamate transporter subtype-1 (GLT-1) (ceftriaxone) are known to inhibit addictive behavior. The purpose of this study was to determine whether the combined action of a low dose of MK-801 and a low dose of ceftriaxone provides better inhibition of the acquisition, extinction, and reinstatement of morphine-induced conditioned place preference (CPP) than either compound alone. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | VENTRAL TEGMENTAL AREA ; BEHAVIORAL SENSITIZATION ; SEEKING BEHAVIOR ; COCAINE-SEEKING ; NMDA RECEPTOR ; UP-REGULATION ; DRUG-SEEKING ; EXPRESSION ; TRANSMISSION ; CUE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000309357800012 |
| 公开日期 | 2015-07-14 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/1579]  |
| 专题 | 武汉物理与数学研究所_磁共振基础研究部 |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 2.Kunming Med Univ, Affiliated Hosp 3, Dept Neurosurg, Kunming 650118, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Brain & Cognit Sci, Kunming 650223, Peoples R China 4.Kunming Gen Hosp Chengdu Mil Reg, Dept Med Imaging, Kunming 650032, Peoples R China 5.Kunming Med Univ, Affiliated Hosp 1, Minimally Invas Neurosurg Dept, Kunming 650032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fan, Yaodong,Niu, Haichen,Rizak, Joshua D.,et al. Combined action of MK-801 and ceftriaxone impairs the acquisition and reinstatement of morphine-induced conditioned place preference, and delays morphine extinction in rats[J]. NEUROSCIENCE BULLETIN,2012,28(5):567-576. |
| APA | Fan, Yaodong.,Niu, Haichen.,Rizak, Joshua D..,Li, Ling.,Wang, Guimei.,...&Yu, Hualin.(2012).Combined action of MK-801 and ceftriaxone impairs the acquisition and reinstatement of morphine-induced conditioned place preference, and delays morphine extinction in rats.NEUROSCIENCE BULLETIN,28(5),567-576. |
| MLA | Fan, Yaodong,et al."Combined action of MK-801 and ceftriaxone impairs the acquisition and reinstatement of morphine-induced conditioned place preference, and delays morphine extinction in rats".NEUROSCIENCE BULLETIN 28.5(2012):567-576. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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