Improve the selectively refocused INEPT pulse sequence for detecting phosphomonoesters and phosphodiesters
文献类型：期刊论文
| 作者 | Mao, Xi-an1,2 |
| 刊名 | MAGNETIC RESONANCE IN MEDICINE
 |
| 出版日期 | 2012-08-01 |
| 卷号 | 68期号:2页码:332-338 |
| 关键词 | 31P magnetic resonance spectroscopy selectively refocused insensitive nuclei enhanced polarization transfer improvement selective refocusing ReBurp |
| 英文摘要 | In application of the 31P selectively refocused insensitive nuclei enhanced polarization transfer (srINEPT) technique to the detection of phosphomono- and diesters in tissues, homonuclear couplings between the CH2O protons and the NCH2 protons seriously attenuate the sensitivity. These couplings can be conventionally removed by two soft 180 degrees pulses in the 1H evolution period which selectively invert the NCH2 magnetizations. However, the srINEPT pulse sequence can be simplified by replacing the pulse train soft 180 degrees-hard 180 degrees-soft 180 degrees with a single soft 180 degrees pulse that selectively inverts the CH2O magnetizations. Theoretical analysis in this study demonstrates the correctness of this approach in principle. Validation on a milk phantom allowed us to investigate and discuss advantages and disadvantages of the proposed srINEPT with respect to the original srINEPT. Furthermore, comparison of different selective pulses made it possible to demonstrate that the proposed srINEPT experiment is not sensitive to errors in pulse length, offset, and B1 field strength of the selective pulse when ReBurp pulse is used for selective refocusing. Magn Reson Med, 2012. (C) 2011 Wiley Periodicals, Inc. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Radiology, Nuclear Medicine & Medical Imaging |
| 研究领域[WOS] | Radiology, Nuclear Medicine & Medical Imaging |
| 关键词[WOS] | MAGNETIC-RESONANCE-SPECTROSCOPY ; P-31 NMR-SPECTROSCOPY ; IN-VIVO ; POLARIZATION TRANSFER ; HUMAN BRAIN ; QUANTIFICATION ; ENHANCEMENT ; METABOLITES ; EXCITATION ; PROTON |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000306318900002 |
| 公开日期 | 2015-07-14 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/1656]  |
| 专题 | 武汉物理与数学研究所_磁共振基础研究部 |
| 作者单位 | 1.Case Western Reserve Univ, Sch Med, Dept Pharmacol, Cleveland, OH 44106 USA 2.Chinese Acad Sci, State Key Lab Magnet Resonance & Atom Mol Phys, Wuhan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mao, Xi-an. Improve the selectively refocused INEPT pulse sequence for detecting phosphomonoesters and phosphodiesters[J]. MAGNETIC RESONANCE IN MEDICINE,2012,68(2):332-338. |
| APA | Mao, Xi-an.(2012).Improve the selectively refocused INEPT pulse sequence for detecting phosphomonoesters and phosphodiesters.MAGNETIC RESONANCE IN MEDICINE,68(2),332-338. |
| MLA | Mao, Xi-an."Improve the selectively refocused INEPT pulse sequence for detecting phosphomonoesters and phosphodiesters".MAGNETIC RESONANCE IN MEDICINE 68.2(2012):332-338. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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