Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway
文献类型：期刊论文
| 作者 | Zhou, Hailong1,2,3,4; Wu, Huifeng1; Liao, Chunyang1; Diao, Xiaoping2; Zhen, Jiping2; Chen, Linlin1; Xue, Qinzhao1 |
| 刊名 | TOXICOLOGY MECHANISMS AND METHODS
 |
| 出版日期 | 2010-07-01 |
| 卷号 | 20期号:6页码:279-286 |
| 关键词 | Persistent organic pollutants AhR pathway toxicology mechanism fish |
| 英文摘要 | With the development of industry and agriculture, the cases of cancer and tumor have been increasing gradually in the last 30 years, and quite a few cases are caused by persistent organic pollutants (POPs), some of them belonging to environmental endocrine disruptors, and they have become ubiquitous in the environment, especially in the aquatic ecosystem; so this issue has aroused the extensive attention of the world. The mechanism of POPs toxicology is very complicated, but it is mainly mediated by the aryl hydrocarbon receptor (AhR) pathway in fish. In order to gain a comprehensive understanding of the AhR pathway, the present paper focuses on reviewing it from four major steps, including formation of cytosolic complex, translocation of AhR, heterodimerization of AhR, and induction of CYP1A. This study summarized the isoform numbers of AhR pathway genes and the expression patterns in the regulation process of POPs toxicology in zebrafish. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000280402000001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/32756]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Hainan Univ, Dept Biotechnol, Coll Agr, Haikou 570228, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Hailong,Wu, Huifeng,Liao, Chunyang,et al. Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway[J]. TOXICOLOGY MECHANISMS AND METHODS,2010,20(6):279-286. |
| APA | Zhou, Hailong.,Wu, Huifeng.,Liao, Chunyang.,Diao, Xiaoping.,Zhen, Jiping.,...&Xue, Qinzhao.(2010).Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway.TOXICOLOGY MECHANISMS AND METHODS,20(6),279-286. |
| MLA | Zhou, Hailong,et al."Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway".TOXICOLOGY MECHANISMS AND METHODS 20.6(2010):279-286. |
入库方式： OAI收割
来源：海洋研究所
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