Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes
文献类型：期刊论文
| 作者 | Mcalonan, Grainne M.1,2; Yu, Kevin K.1; Chan, Raymond C. K.3 ; Chua, Siew E.1,2; Cheung, Charlton1
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| 刊名 | CHINESE SCIENCE BULLETIN
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| 出版日期 | 2011-11-01 |
| 卷号 | 56期号:32页码:3376-3381 |
| 关键词 | autism schizophrenia bipolar grey matter ALE meta-analysis |
| ISSN号 | 1001-6538 |
| 产权排序 | 3 |
| 通讯作者 | Mcalonan, GM (reprint author), Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China. |
| 英文摘要 | The term "neurodevelopmental disorder" broadly encompasses conditions thought to arise early in development and includes schizophrenia, bipolar disorder and autism among others. These conditions share a number of genetic and environmental risk factors postulated to lead to common difficulties in socio-emotional processing, communication and cognitive function. The alternative position is that, while the same traits are affected across these conditions, the nature or direction in which they are modified may be distinct. MRI studies provide a rapidly expanding and rich database which we propose can be used to contribute to this debate. Anatomical likelihood estimation (ALE) is a method of meta-analysis applied to voxel-based MRI studies. We have adapted this method to explore the extent to which schizophrenia and bipolar disorder and schizophrenia and autism share a common brain structural phenotype. We will review this work here and discuss whether there is sufficient other evidence to justify a common framework for further research into the inter-relatedness of such conditions. |
| 学科主题 | Cognitive neuroscience |
| 收录类别 | SCI |
| 项目简介 | The Autism Research Group in the Department of Psychiatry University of Hong Kong is grateful for donation funding from ING Asia/Pacific. |
| 原文出处 | http://www.cnki.com.cn/Article/CJFDTotal-JXTW201132006.htm |
| 语种 | 英语 |
| WOS记录号 | WOS:000296641800004 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/11877]  |
| 专题 | 心理研究所_脑与认知科学国家重点实验室 |
| 作者单位 | 1.Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China 2.Univ Hong Kong, State Key Lab Brain & Cognit Sci, Hong Kong, Hong Kong, Peoples R China 3.Chinese Acad Sci, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mcalonan, Grainne M.,Yu, Kevin K.,Chan, Raymond C. K.,et al. Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes[J]. CHINESE SCIENCE BULLETIN,2011,56(32):3376-3381. |
| APA | Mcalonan, Grainne M.,Yu, Kevin K.,Chan, Raymond C. K.,Chua, Siew E.,&Cheung, Charlton.(2011).Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes.CHINESE SCIENCE BULLETIN,56(32),3376-3381. |
| MLA | Mcalonan, Grainne M.,et al."Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes".CHINESE SCIENCE BULLETIN 56.32(2011):3376-3381. |
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来源：心理研究所
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