Development of a Biomedical Micro/Nano Robot for Drug Delivery
文献类型：期刊论文
| 作者 | Xie, Zhihong
|
| 刊名 | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
 |
| 出版日期 | 2015-04 |
| 卷号 | 15期号:4页码:3126-3129 |
| 关键词 | Micro/Nano Robot Bacterial Flagellar Motor Liposome Antibody Drug Delivery System |
| ISSN号 | 1533-4880 |
| 产权排序 | [Zhang, Zhenhai; Li, Kejie] Beijing Inst Technol, Sch Mechatron Engn, Beijing 100081, Peoples R China; [Li, Zhifei] Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China; [Yu, Wei] Shanghai Second Polytech Univ, Sch Urban Dev & Environm Engn, Shanghai 201209, Peoples R China; [Xie, Zhihong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China |
| 通讯作者 | Xie, ZH (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China. |
| 中文摘要 | Flagellated bacteria have been utilized as potential swimming micro-robotic bodies for propulsion of spherical liposome by attaching several bacteria on their surface. Liposome as a drug delivery vehicle can contain biologically active compounds. In this work, the antibody binding technique is developed to attach bacteria to liposome's surface. Consequently, the stochastic effect of bacterial propulsion of liposome is investigated analytically and experimentally. It is shown that the mobility of liposome with bacteria was higher than that of liposome without bacteria. Experimental data matches well with statistical calculation. |
| 学科主题 | Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter |
| 研究领域[WOS] | National Natural Science Foundation of China [61273346, 31370108, 51106093, 50876058] ; Hundred Talents Program of Chinese Academy of Sciences [1103000003] ; Key Projects in the Yantai Science and Technology Pillar Program [2013JH021] ; National Defense Major Fundamental Research Program of China [C x x 20110003] ; National Defense Key Fundamental Research Program of China [A x x 20110005, A x x 20132010] ; Specialized Research Fund for the Doctoral Program of Higher Education [20121101120009] ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, Excellent Young Scholars Research Fund of Beijing Institute of Technology [2012YG0203] ; Program for the Fundamental Research of Beijing Institute of Technology [2013CX04031, 2011CX02023, 2014CX x x x x] ; Program of Introducing Talents of Discipline to University, China [B08043] |
| 关键词[WOS] | FLAGELLA ; MOTOR |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347435100080 |
| 公开日期 | 2015-08-04 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/8510]  |
| 专题 | 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 推荐引用方式 GB/T 7714 | Xie, Zhihong. Development of a Biomedical Micro/Nano Robot for Drug Delivery[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2015,15(4):3126-3129. |
| APA | Xie, Zhihong.(2015).Development of a Biomedical Micro/Nano Robot for Drug Delivery.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,15(4),3126-3129. |
| MLA | Xie, Zhihong."Development of a Biomedical Micro/Nano Robot for Drug Delivery".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15.4(2015):3126-3129. |
入库方式： OAI收割
来源：烟台海岸带研究所
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