中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group

文献类型:期刊论文

作者Hu, Yunxia1,2; Zhang, Jun3; Yu, Chunwei3; Li, Qing1; Dong, Fang1; Wang, Gang1; Guo, Zhanyong1
刊名INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
出版日期2014-09-01
卷号70页码:44-49
关键词Inulin derivatives Antioxidant properties Amino-pyridines
ISSN号0141-8130
产权排序[Hu, Yunxia; Li, Qing; Dong, Fang; Wang, Gang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Hu, Yunxia] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Zhang, Jun; Yu, Chunwei] Hainan Med Coll, Sch Trop & Lab Med, Environm Monitoring Lab, Haikou 571199, Peoples R China
通讯作者Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. zhanyongguo@hotmail.com
英文摘要A series of novel inulin derivatives were synthesized via reaction of chloracetyl inulin (CAR) with amino-pyridines, including 2-(2-amino-pyridyl)acetyl inulin chloride (2APAIL), 2-(3-amino-pyridyl)acetyl inulin chloride (3APAIL), 2-(4-amino-pyridyl)acetyl inulin chloride (4APAIL), 2-(2,3-diaminopyridyl)acetyl inulin chloride (2,3DAPAIL), and 2-(3,4-diamino-pyridyl)acetyl inulin (3,4DAPAIL). The antioxidant property of the products and 2-pyridylacetyl inulin chloride (PAIL) against hydroxyl radicals ((OH)-O-center dot), superoxide radicals (O-2(center dot)), and DPPH radicals (DPPH center dot) were evaluated in vitro, respectively. Results showed that 4APAIL and 3,4DAPAIL exhibited remarkable improvement on scavenging (OH)-O-center dot and DPPH center dot, which can scavenge the radical of (OH)-O-center dot completely at 0.4 mg/mL. Besides, the scavenging activity of 2,3DAPAIL to O-2(center dot) was excellent among all of the tested samples, reaching 85% at 1.6 mg/mL. These data indicate that all of the inulin derivatives have better antioxidant activities than inulin, and the scavenging effect indices are affected by the number and position of the amino group on pyridine grafted to the inulin derivatives. (C) 2014 Elsevier B.V. All rights reserved.
学科主题Biochemistry & Molecular Biology
研究领域[WOS]Biochemistry & Molecular Biology
关键词[WOS]IN-VITRO ; ANTIFUNGAL ACTIVITY ; CHITOSAN DERIVATIVES ; POLYSACCHARIDES ; FRUCTANS ; DESIGN ; CHITIN
收录类别SCI
语种英语
WOS记录号WOS:000342478800006
源URL[http://ir.yic.ac.cn/handle/133337/8531]  
专题烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
烟台海岸带研究所_污染过程与控制实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Hainan Med Coll, Sch Trop & Lab Med, Environm Monitoring Lab, Haikou 571199, Peoples R China
推荐引用方式
GB/T 7714
Hu, Yunxia,Zhang, Jun,Yu, Chunwei,et al. Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2014,70:44-49.
APA Hu, Yunxia.,Zhang, Jun.,Yu, Chunwei.,Li, Qing.,Dong, Fang.,...&Guo, Zhanyong.(2014).Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,70,44-49.
MLA Hu, Yunxia,et al."Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 70(2014):44-49.

入库方式: OAI收割

来源:烟台海岸带研究所

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