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Fluorescent probes for hydrogen sulfide detection and bioimaging

文献类型:期刊论文

作者Yu, Fabiao1; Han, Xiaoyue1,2; Chen, Lingxin1
刊名CHEMICAL COMMUNICATIONS
出版日期2014-10-21
卷号50期号:82页码:12234-12249
关键词TURN-ON PROBE LIVING CELLS SELECTIVE DETECTION HYPOBROMOUS ACID OXIDATIVE STRESS HIGH-SENSITIVITY AQUEOUS-SOLUTION SO2 DERIVATIVES H2S PRODUCTION REDOX CYCLE
ISSN号1359-7345
产权排序[Yu, Fabiao; Han, Xiaoyue; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Han, Xiaoyue] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
中文摘要In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.
英文摘要In comparison with other biological detection technologies, fluorescence bioimaging technology has become a powerful supporting tool for intracellular detection, and can provide attractive facilities for investigating physiological and pathological processes of interest with high spatial and temporal resolution, less invasiveness, and a rapid response. Due to the versatile roles of hydrogen sulfide (H2S) in cellular signal transduction and intracellular redox status regulation, fluorescent probes for the detection of this third signalling gasotransmitter have rapidly increased in number in recent years. These probes can offer powerful means to investigate the physiological actions of H2S in its native environments without disturbing its endogenous distribution. In this feature article, we address the synthesis and design strategies for the development of fluorescent probes for H2S based on the reaction type between H2S and the probes. Moreover, we also highlight fluorescent probes for other reactive sulfur species, such as sulfane sulfurs and SO2 derivatives.
学科主题Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]TURN-ON PROBE ; LIVING CELLS ; SELECTIVE DETECTION ; HYPOBROMOUS ACID ; OXIDATIVE STRESS ; HIGH-SENSITIVITY ; AQUEOUS-SOLUTION ; SO2 DERIVATIVES ; H2S PRODUCTION ; REDOX CYCLE
收录类别SCI
语种英语
WOS记录号WOS:000342887100002
源URL[http://ir.yic.ac.cn/handle/133337/8700]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Yu, Fabiao,Han, Xiaoyue,Chen, Lingxin. Fluorescent probes for hydrogen sulfide detection and bioimaging[J]. CHEMICAL COMMUNICATIONS,2014,50(82):12234-12249.
APA Yu, Fabiao,Han, Xiaoyue,&Chen, Lingxin.(2014).Fluorescent probes for hydrogen sulfide detection and bioimaging.CHEMICAL COMMUNICATIONS,50(82),12234-12249.
MLA Yu, Fabiao,et al."Fluorescent probes for hydrogen sulfide detection and bioimaging".CHEMICAL COMMUNICATIONS 50.82(2014):12234-12249.

入库方式: OAI收割

来源:烟台海岸带研究所

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