中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Fluorescent Probes for Hydrogen Sulfide Detection

文献类型:期刊论文

作者Gao Min1,2; Yu Fabiao1; Chen Lingxin1
刊名PROGRESS IN CHEMISTRY
出版日期2014-06-01
卷号26期号:6页码:1065-1078
关键词hydrogen sulfide fluorescent molecular probe reactive sulfur species gasotransmitter visual detection
ISSN号1005-281X
产权排序[Gao Min; Yu Fabiao; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Gao Min] Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China
通讯作者Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
中文摘要Following carbon monoxide and nitric oxide, hydrogen sulfide (H2S) is found to be the third endogenous gasotransmitter, which provides the regulation significance of physiological and pathological processes in the cardiovascular and nervous systems. Therefore, the selective recognition and detection of H2S are of importance. Fluorescent probe method, among biological detection technologies, is an indispensable technique for the biological species analysis, and that is highlighted by its good selectivity, high sensitivity, noninvasive detection, and real-time monitoring in situ. Recently, the development of fluorescent probes for intracellular H2S detection has been becoming one of the hot topics. Herein, the progress during the last three years of fluorescent molecular probes based on the small molecules for H2S detection are reviewed. These fluorescent probes are classified and concluded according to the different types of chemical reaction with H2S, and then arranged specifically by the fluorophores in different type. The design concepts of molecular structures, detection mechanism and biological applications of these probes are introduced. In addition, the relationship between molecular structures and properties while testing are elucidated. Finally, the challenge and application prospects for the development of hydrogen sulfide fluorescent probes are also discussed.
英文摘要Following carbon monoxide and nitric oxide, hydrogen sulfide (H2S) is found to be the third endogenous gasotransmitter, which provides the regulation significance of physiological and pathological processes in the cardiovascular and nervous systems. Therefore, the selective recognition and detection of H2S are of importance. Fluorescent probe method, among biological detection technologies, is an indispensable technique for the biological species analysis, and that is highlighted by its good selectivity, high sensitivity, noninvasive detection, and real-time monitoring in situ. Recently, the development of fluorescent probes for intracellular H2S detection has been becoming one of the hot topics. Herein, the progress during the last three years of fluorescent molecular probes based on the small molecules for H2S detection are reviewed. These fluorescent probes are classified and concluded according to the different types of chemical reaction with H2S, and then arranged specifically by the fluorophores in different type. The design concepts of molecular structures, detection mechanism and biological applications of these probes are introduced. In addition, the relationship between molecular structures and properties while testing are elucidated. Finally, the challenge and application prospects for the development of hydrogen sulfide fluorescent probes are also discussed.
学科主题Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]TURN-ON PROBE ; LIVING CELLS ; IN-VIVO ; HIGH SELECTIVITY ; H2S PRODUCTION ; REDOX CYCLE ; SE-BODIPY ; SENSOR ; RECOGNITION ; BISULFITE
收录类别SCI
语种英语
WOS记录号WOS:000338393000015
源URL[http://ir.yic.ac.cn/handle/133337/8739]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China
推荐引用方式
GB/T 7714
Gao Min,Yu Fabiao,Chen Lingxin. Fluorescent Probes for Hydrogen Sulfide Detection[J]. PROGRESS IN CHEMISTRY,2014,26(6):1065-1078.
APA Gao Min,Yu Fabiao,&Chen Lingxin.(2014).Fluorescent Probes for Hydrogen Sulfide Detection.PROGRESS IN CHEMISTRY,26(6),1065-1078.
MLA Gao Min,et al."Fluorescent Probes for Hydrogen Sulfide Detection".PROGRESS IN CHEMISTRY 26.6(2014):1065-1078.

入库方式: OAI收割

来源:烟台海岸带研究所

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