Fluorescent Probes for Reactive Nitrogen Species
文献类型：期刊论文
| 作者 | Jing Xiaotong1,2; Yu Fabiao1; Chen Lingxin1
|
| 刊名 | PROGRESS IN CHEMISTRY
 |
| 出版日期 | 2014-05-01 |
| 卷号 | 26期号:5页码:866-878 |
| 关键词 | reactive nitrogen species fluorescent probe bioimaging nitric oxide peroxynitrite |
| ISSN号 | 1005-281X |
| 其他题名 | 检测活性氮物种的荧光探针 |
| 产权排序 | [Jing Xiaotong; Yu Fabiao; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Jing Xiaotong] Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China |
| 通讯作者 | Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. lxchen@yic.ac.cn |
| 中文摘要 | It is generally established that the intracellular reactive nitrogen species (RNS) which contain nitrogen atoms are one class of highly chemical active species. These species have attracted increasing attention and become an active research field based on their key roles in special functions during a series of physiological and pathological processes. In order to elucidate these roles of RNS, the design and development technology for selective and sensitive detection to RNS in vivo are crucial. Advanced with high sensitivity, good selectivity, noninvasive detection and real-time visualization in situ, fluorescent probes provide facilitative and effective chemical approaches in modern biochemistry analysis. Progress in the field of fluorescent probes for RNS promises to advance our knowledge of essential cellular signal transduction during the varieties of physiological and pathological processes, which is indicated in human health and disease. According to the current situation, we review the past four years' latest five types of RNS probes for nitric oxide (NO), peroxynitrite (ONOO-), nitroxyl (HNO), nitrite (NO2-) and nitrogen dioxide (NO2). In this article, the design strategies, fluorescent response mechanisms and biological applications of the probes are discussed. Finally, the prospect to design and applications of probes is given. |
| 英文摘要 | It is generally established that the intracellular reactive nitrogen species (RNS) which contain nitrogen atoms are one class of highly chemical active species. These species have attracted increasing attention and become an active research field based on their key roles in special functions during a series of physiological and pathological processes. In order to elucidate these roles of RNS, the design and development technology for selective and sensitive detection to RNS in vivo are crucial. Advanced with high sensitivity, good selectivity, noninvasive detection and real-time visualization in situ, fluorescent probes provide facilitative and effective chemical approaches in modern biochemistry analysis. Progress in the field of fluorescent probes for RNS promises to advance our knowledge of essential cellular signal transduction during the varieties of physiological and pathological processes, which is indicated in human health and disease. According to the current situation, we review the past four years' latest five types of RNS probes for nitric oxide (NO), peroxynitrite (ONOO-), nitroxyl (HNO), nitrite (NO2-) and nitrogen dioxide (NO2). In this article, the design strategies, fluorescent response mechanisms and biological applications of the probes are discussed. Finally, the prospect to design and applications of probes is given. |
| 学科主题 | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | NITRIC-OXIDE PRODUCTION ; LIVING CELLS ; MACROPHAGE CELLS ; AQUEOUS-SOLUTION ; NITROXYL HNO ; PEROXYNITRITE DETECTION ; SELECTIVE DETECTION ; BIOLOGICAL-ACTIVITY ; LUMINESCENT PROBES ; IMAGING AGENT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000336560200015 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/8750]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol Shandong, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jing Xiaotong,Yu Fabiao,Chen Lingxin. Fluorescent Probes for Reactive Nitrogen Species[J]. PROGRESS IN CHEMISTRY,2014,26(5):866-878. |
| APA | Jing Xiaotong,Yu Fabiao,&Chen Lingxin.(2014).Fluorescent Probes for Reactive Nitrogen Species.PROGRESS IN CHEMISTRY,26(5),866-878. |
| MLA | Jing Xiaotong,et al."Fluorescent Probes for Reactive Nitrogen Species".PROGRESS IN CHEMISTRY 26.5(2014):866-878. |
入库方式： OAI收割
来源：烟台海岸带研究所
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