Surface-enhanced Raman scattering on a zigzag microfluidic chip: towards high-sensitivity detection of As(III)ions
文献类型：期刊论文
| 作者 | Qi, Nan1,2; Li, Bowei2 ; You, Huiyan1; Zhang, Wei2,3; Fu, Longwen2; Wang, Yunqing2; Chen, Lingxin2
|
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2014 |
| 卷号 | 6期号:12页码:4077-4082 |
| 关键词 | SILVER NANOPARTICLES SPECTROSCOPY INJECTION IONS ELECTROPHORESIS MICROCHANNEL COLLOIDS SYSTEMS SCALE |
| ISSN号 | 1759-9660 |
| 产权排序 | [Qi, Nan; You, Huiyan] Dalian Univ, Environm & Chem Engn Coll, Dalian 116600, Peoples R China; [Qi, Nan; Li, Bowei; Zhang, Wei; Fu, Longwen; Wang, Yunqing; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Zhang, Wei] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 通讯作者 | You, HY (reprint author), Dalian Univ, Environm & Chem Engn Coll, Dalian 116600, Peoples R China. dlyhy@dicp.ac.cn ; lxchen@yic.ac.cn |
| 中文摘要 | In this study, a microfluidic platform was combined with surface-enhanced Raman scattering (SERS) to implement the rapid quantitative detection of As(III) ions in a continuous flow. Silver nanoparticles (AgNPs) were used as the SERS enhancement substrate, and glutathione (GSH) with 4-mercaptopyridine (4-MPY) was conjugated on the surface of the AgNPs. When As(III) ions encountered GSH/4-MPY functionalized AgNPs, the original monodispersed probes would aggregate because As(III) ions had a strong affinity to the GSH. As a result, Raman signals of 4-MPY adsorbed on the surface of the AgNPs were improved and the As(III) ions could be detected. Due to the advantages of microfluidics technology combined with SERS detection, the highly sensitive and reproducible analysis of As(III) ions was realized in several minutes. The proposed method allowed the quantitative analysis of As(III) ions with a linear range (3 to 200 ppb), and the limit of detection (LOD) of the As(III) ions was determined to be 0.67 ppb. The real water sample was also analyzed to confirm the practicability of the method and the consumption of several microliters of the sample was found to be environmentally friendly. This method also showed great potential in applying SERS combined with a lab-on-a-chip technique in the area of environmental monitoring with a high sensitivity and in an environmentally friendly way. |
| 英文摘要 | In this study, a microfluidic platform was combined with surface-enhanced Raman scattering (SERS) to implement the rapid quantitative detection of As(III) ions in a continuous flow. Silver nanoparticles (AgNPs) were used as the SERS enhancement substrate, and glutathione (GSH) with 4-mercaptopyridine (4-MPY) was conjugated on the surface of the AgNPs. When As(III) ions encountered GSH/4-MPY functionalized AgNPs, the original monodispersed probes would aggregate because As(III) ions had a strong affinity to the GSH. As a result, Raman signals of 4-MPY adsorbed on the surface of the AgNPs were improved and the As(III) ions could be detected. Due to the advantages of microfluidics technology combined with SERS detection, the highly sensitive and reproducible analysis of As(III) ions was realized in several minutes. The proposed method allowed the quantitative analysis of As(III) ions with a linear range (3 to 200 ppb), and the limit of detection (LOD) of the As(III) ions was determined to be 0.67 ppb. The real water sample was also analyzed to confirm the practicability of the method and the consumption of several microliters of the sample was found to be environmentally friendly. This method also showed great potential in applying SERS combined with a lab-on-a-chip technique in the area of environmental monitoring with a high sensitivity and in an environmentally friendly way. |
| 学科主题 | Chemistry, Analytical; Food Science & Technology; Spectroscopy |
| 研究领域[WOS] | Chemistry ; Food Science & Technology ; Spectroscopy |
| 关键词[WOS] | SILVER NANOPARTICLES ; SPECTROSCOPY ; INJECTION ; IONS ; ELECTROPHORESIS ; MICROCHANNEL ; COLLOIDS ; SYSTEMS ; SCALE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000337121800023 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/8784]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 烟台海岸带研究所_山东省海岸带环境工程技术研究中心 |
| 作者单位 | 1.Dalian Univ, Environm & Chem Engn Coll, Dalian 116600, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qi, Nan,Li, Bowei,You, Huiyan,et al. Surface-enhanced Raman scattering on a zigzag microfluidic chip: towards high-sensitivity detection of As(III)ions[J]. ANALYTICAL METHODS,2014,6(12):4077-4082. |
| APA | Qi, Nan.,Li, Bowei.,You, Huiyan.,Zhang, Wei.,Fu, Longwen.,...&Chen, Lingxin.(2014).Surface-enhanced Raman scattering on a zigzag microfluidic chip: towards high-sensitivity detection of As(III)ions.ANALYTICAL METHODS,6(12),4077-4082. |
| MLA | Qi, Nan,et al."Surface-enhanced Raman scattering on a zigzag microfluidic chip: towards high-sensitivity detection of As(III)ions".ANALYTICAL METHODS 6.12(2014):4077-4082. |
入库方式： OAI收割
来源：烟台海岸带研究所
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