Antibacterial constituents from Melodinus suaveolens
文献类型：期刊论文
| 作者 | Li, J. L.; Lunga, P. K.; Zhao, Y. L.; Qin, X. J.; Luo, X. D. |
| 刊名 | CHINESE JOURNAL OF NATURAL MEDICINES
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| 出版日期 | 2015 |
| 卷号 | 13期号:4页码:307-310 |
| 关键词 | Melodinus suaveolens Apocynaceae Non-alkaloidal chemical constituents Meningitis Antibacterial activity |
| 通讯作者 | Liu,YP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; xdluo@mail.kib.ac.cn ; liuyap-ing@mail.kib.ac.cn |
| 英文摘要 | To investigate the non-alkaloidal chemical constituents of the stems and leaves of Melodinus suaveolens and their antibacterial activities. Compounds were isolated and purified by repeated silica gel, Sephadex LH-20, RP18, and preparative HPLC. Their structures were elucidated by comparison with published spectroscopic data, as well as on the basis of extensive spectroscopic analysis. The antibacterial screening assays were performed by the dilution method. Fourteen compounds were isolated, and identified as lycopersene (1). betulinic aldehyde (2), 3 beta-acctoxy-22,23,24,25,26,27-hexanordammaran-20-one(3), 3a-acetyl-2, 3, 5-trimethyl-7a-hydroxy-5-(4,8, 12-trimethyl-tridecanyl)-1,3a, 5,6,7,7a-hexahydro- 4-oxainden-1-one (4), 3 beta-hydroxy-28-norlup-20(29)-ene-17 beta-hydroperoxide (5), 3 beta-hydroxy-28-norlup-20(29)-ene-17 alpha-hydroperoxide (6), beta-sitosterol (7), 28-nor-urs-12-ene-3 beta, 17 beta-diol (8), alpha-amyrin (9), ergosta-4,6,8(14) 22-tetraen-3-one (10), 3 beta-hydroxy-urs-11-en-28,13 beta-olide (11), betulin (12), obtusalin (13), and ursolic acid (14), Among the isolates,. compounds 1, 2. 6, 8, 10, and 14 showed potent antibacterial activities against the four bacteria, This is the first report of the antibacterial activity of the constituents of Melodinus suaveolens |
| 学科主题 | Integrative & Complementary Medicine; Pharmacology & Pharmacy |
| 类目[WOS] | Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| 关键词[WOS] | ALKALOIDS ; TRITERPENOIDS ; LEAVES ; ASSIGNMENTS ; OXIDATION ; TISSUE ; FRUIT ; RAT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000366434900009 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/21348]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, J. L.,Lunga, P. K.,Zhao, Y. L.,et al. Antibacterial constituents from Melodinus suaveolens[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2015,13(4):307-310. |
| APA | Li, J. L.,Lunga, P. K.,Zhao, Y. L.,Qin, X. J.,&Luo, X. D..(2015).Antibacterial constituents from Melodinus suaveolens.CHINESE JOURNAL OF NATURAL MEDICINES,13(4),307-310. |
| MLA | Li, J. L.,et al."Antibacterial constituents from Melodinus suaveolens".CHINESE JOURNAL OF NATURAL MEDICINES 13.4(2015):307-310. |
入库方式： OAI收割
来源：昆明植物研究所
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