Polychlorinated dibenzo-p-dioxins and dibenzofurans in blood and breast milk samples from residents of a schistosomiasis area with Na-PCP application in China
文献类型：期刊论文
| 作者 | Xiao, Ke ; Zhao, Xingru ; Liu, Zhengtao ; Zhang, Bing ; Fang, Liping ; Liu, Wenbin ; Zheng, Minghui |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2010-04 |
| 卷号 | 79期号:7页码:740-744 |
| 关键词 | PCDD/Fs DNA damage Blood Breast milk Sodium pentachlorophenate Dongting Lake |
| 中文摘要 | Schistosomiasis has prevailed in some areas of China for a long time. Chinese technical sodium pentachlorophenate (Na-PCP) has been used to control the spread of snail-borne schistosomiasis since the 1960s. Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), impurities contained in the Na-PCP, enter the soil and may accumulate in the food chain. In order to evaluate their potentially harmful effects on local residents, 50 breast milk samples and 20 blood samples were collected in 2004 from residents in the Dongting Lake area, one of China's known schistosomiasis areas. Levels of 17 PCDD/F congeners were measured in all samples, and DNA damage was simultaneously assessed in blood samples. The PCDD/F congener distribution patterns in human tissue samples from the Dongting Lake area were similar to those in Na-PCP, and the octachlorodibenzodioxin (OCDD) congener was predominant in all samples. We also had a primary investigation that the breast milk WHO-TEQ associated with some factors such as: age, dietary habit, body mass index (BMI) and the total menses times. In blood samples, the samples with higher OCDD level had higher DDS (DNA damage score) values than those samples with low OCDD level, which indicated that the higher DNA damage value in general population might be caused directly or indirectly by PCDD/Fs. The results also indicated that the WHO-TEQ values in blood were associated with age (r = 0.6, p = 0.007). (C) 2010 Elsevier Ltd. All rights reserved. |
| WOS记录号 | WOS:000278131100009 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/21123]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Xiao, Ke,Zhao, Xingru,Liu, Zhengtao,et al. Polychlorinated dibenzo-p-dioxins and dibenzofurans in blood and breast milk samples from residents of a schistosomiasis area with Na-PCP application in China[J]. CHEMOSPHERE,2010,79(7):740-744. |
| APA | Xiao, Ke.,Zhao, Xingru.,Liu, Zhengtao.,Zhang, Bing.,Fang, Liping.,...&Zheng, Minghui.(2010).Polychlorinated dibenzo-p-dioxins and dibenzofurans in blood and breast milk samples from residents of a schistosomiasis area with Na-PCP application in China.CHEMOSPHERE,79(7),740-744. |
| MLA | Xiao, Ke,et al."Polychlorinated dibenzo-p-dioxins and dibenzofurans in blood and breast milk samples from residents of a schistosomiasis area with Na-PCP application in China".CHEMOSPHERE 79.7(2010):740-744. |
入库方式： OAI收割
来源：生态环境研究中心
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