Pseudo-template molecularly imprinted polymer for selective screening of trace beta-lactam antibiotics in river and tap water
文献类型：期刊论文
| 作者 | Yin, Junfa; Meng, Zihui; Du, Mingjun; Liu, Cong; Song, Maoyong; Wang, Hailin |
| 刊名 | JOURNAL OF CHROMATOGRAPHY A
 |
| 出版日期 | 2010-08-15 |
| 卷号 | 1217期号:33页码:5420-5426 |
| 关键词 | beta-Lactam antibiotics Molecularly imprinted polymer Pseudo template Photopolymerization Molecularly imprinted solid-phase extraction |
| 中文摘要 | To assess the potential risks associated with the environmental exposure of beta-lactam antibiotics (BLAs), the monitoring of the occurrence, distribution, and fate of these emerging contaminants in the environment is required. Herein, we demonstrate a molecularly imprinted solid-phase extraction (MISPE) method for selective and reliable screening of trace BLAs in river and tap water. By developing a low-temperature photopolymerization, highly selective molecularly imprinted polymers (MIPs) for five BLAs (penicillin G, amoxicillin, ampicillin, nafcillin and mezlocillin) were synthesized. Nafcillin was chosen as a pseudo template to make the MIP sorbent (Nafc-MIP), which was used in pseudo-template MISPE for preconcentration of the other four BLAs from river and tap water. The application of pseudo-template MISPE overcomes the template bleeding, which significantly elevates the sample background and restricts the application of MIP for detection of the target BLA below 2 mu g/L. The average recoveries of BLAs are in the range of 60-90% when Nafc-MIP was adopted as the selective MISPE sorbent. The developed method was validated, and applied to the screening of trace beta-lactam antibiotics in river and tap water. The linearity of the calibration curve for each BLA was observed over the range of 0.1-20 mu g/L (r > 0.998). The beta-lactam antibiotics were found within the range of 0-9.56 mu g/L in river water at the downstream of antibiotics manufacturers, and none were detected in the tap water. (C) 2010 Elsevier B.V. All rights reserved. |
| WOS记录号 | WOS:000280970500013 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/21131]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Yin, Junfa,Meng, Zihui,Du, Mingjun,et al. Pseudo-template molecularly imprinted polymer for selective screening of trace beta-lactam antibiotics in river and tap water[J]. JOURNAL OF CHROMATOGRAPHY A,2010,1217(33):5420-5426. |
| APA | Yin, Junfa,Meng, Zihui,Du, Mingjun,Liu, Cong,Song, Maoyong,&Wang, Hailin.(2010).Pseudo-template molecularly imprinted polymer for selective screening of trace beta-lactam antibiotics in river and tap water.JOURNAL OF CHROMATOGRAPHY A,1217(33),5420-5426. |
| MLA | Yin, Junfa,et al."Pseudo-template molecularly imprinted polymer for selective screening of trace beta-lactam antibiotics in river and tap water".JOURNAL OF CHROMATOGRAPHY A 1217.33(2010):5420-5426. |
入库方式： OAI收割
来源：生态环境研究中心
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