Optimizing ultra performance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design
文献类型：期刊论文
| 作者 | Li, Peng; Xu, Gang ; Li, Shao-Ping; Wang, Yi-Tao; Fan, Tai-Ping; Zhao, Qin-Shi; Zhang, Qing-Wen
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| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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| 出版日期 | 2008-02-27 |
| 卷号 | 56期号:4页码:1164-1171 |
| 关键词 | ultraperformance liquid chromatography (UPLC) diterpenoid Salvia miltiorrhiza central composite design |
| 英文摘要 | A rapid, sensitive, reproducible, and accurate ultraperformance liquid chromatographic (UPLC) method was developed for the simultaneous determination of 10 diterpenoid compounds (tanshinone 1, tanshinone IIA, cryptotanshinone, dihydrotanshinone I, 1,2-dihydrotanshinquinone, methylenetanshinquinone, miltirone, 5,6-dehydrosugiol, sugiol, and przewalskin) in Salvia miltiorrhiza for the first time. Central composite design was applied as a powerful tool to optimize the most dominant parameters that influence the resolution of UPLC, that is, gradient, flow rate, and column temperature. Under optimum conditions, all peaks except 1,2-dihydrotanshinquinone and methylenetanshinquinone could be baseline separated within 8 min. Furthermore, the contents of these compounds in S. miltiorrhiza samples collected from different provinces of China have also been compared. The results showed that UPLC is one of the most efficient methods for the analysis of diterpenoid compounds in S. miltiorrhiza and that it is a potential method for quality control of this valuable traditional Chinese medicine. |
| 类目[WOS] | Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology |
| 研究领域[WOS] | Agriculture ; Chemistry ; Food Science & Technology |
| 关键词[WOS] | CHINESE MEDICINAL PREPARATIONS ; TANSHINONE-IIA ; BUNGE ; DANSHEN ; CRYPTOTANSHINONE ; COMPONENTS ; CELLS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000253321200002 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/23863]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Univ Macau, Inst Chinese Med Sci, Macao, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Peoples R China 3.Univ Cambridge, Dept Pharmacol, Angiogenesis & Tradit Chinese Med Lab, Cambridge CB2 1PD, England |
| 推荐引用方式 GB/T 7714 | Li, Peng,Xu, Gang,Li, Shao-Ping,et al. Optimizing ultra performance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2008,56(4):1164-1171. |
| APA | Li, Peng.,Xu, Gang.,Li, Shao-Ping.,Wang, Yi-Tao.,Fan, Tai-Ping.,...&Zhang, Qing-Wen.(2008).Optimizing ultra performance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,56(4),1164-1171. |
| MLA | Li, Peng,et al."Optimizing ultra performance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 56.4(2008):1164-1171. |
入库方式： OAI收割
来源：昆明植物研究所
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