Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD
文献类型：期刊论文
| 作者 | Ge, Guang-Bo1,2; Liang, Si-Cheng1; Hu, Ying1; Liu, Xing-Bao1; Mao, Yu-Xi1,2; Zhang, Yan-Yan1,2; Luan, Hong-Wei1; Qiu, Ming-Hua3 ; Yang, Ling1
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| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2010-10-01 |
| 卷号 | 76期号:15页码:1773-1777 |
| 关键词 | Taxaceae Taxus yew taxane paclitaxel target analysis |
| 英文摘要 | The distribution and level of yew constituents vary with species and tissues. In this study, a rapid and valid method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for simultaneous determination of paclitaxel and its six semisynthesis precursors in needles and hair roots from various Taxus species. All target analytes could be identified by comparing their retention times as well as UV and MS spectra with authentic standards, while seven valuable taxanes in botanical samples can be rapidly determined by UFLC-DAD with excellent sensitivity. Analysis of more than one hundred yew samples from nine species showed significant variations in distribution and content of seven evaluated taxanes. Thus, different developmental schemes should be used for better utilization of various yew resources. |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | IONIZATION MASS-SPECTROMETRY ; BASIC TAXOID CONTENTS ; LIQUID-CHROMATOGRAPHY ; PACLITAXEL ; EFFICIENT ; DITERPENOIDS ; CONVERSION ; NEEDLES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000283917300028 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/23906]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China 3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ge, Guang-Bo,Liang, Si-Cheng,Hu, Ying,et al. Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD[J]. PLANTA MEDICA,2010,76(15):1773-1777. |
| APA | Ge, Guang-Bo.,Liang, Si-Cheng.,Hu, Ying.,Liu, Xing-Bao.,Mao, Yu-Xi.,...&Yang, Ling.(2010).Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD.PLANTA MEDICA,76(15),1773-1777. |
| MLA | Ge, Guang-Bo,et al."Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD".PLANTA MEDICA 76.15(2010):1773-1777. |
入库方式： OAI收割
来源：昆明植物研究所
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