Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae
文献类型：期刊论文
| 作者 | Zhu, Kevin Y.1,2; Fu, Q.1,2; Xie, Heidi Q.1,2; Xu, Sherry L.1,2; Cheung, Anna W. H.1,2; Zheng, Ken Y. Z.1,2; Luk, Wilson K. W.1,2; Choi, Roy C. Y.1,2; Lau, David T. W.1,2; Dong, Tina T. X.1,2 |
| 刊名 | JOURNAL OF SEPARATION SCIENCE
 |
| 出版日期 | 2010-12-01 |
| 卷号 | 33期号:23-24页码:3666-3674 |
| 关键词 | Chemical assessment Depression Herbal mixture LC-MS TCM |
| 英文摘要 | Kaixinsan is an ancient Chinese herbal decoction mainly prescribed for patients suffering from mental depression. This decoction was created by Sun Si-miao of Tang Dynasty (A.D. 600) in ancient China, and was composed of four herbs: Radix and Rhizome Ginseng, Radix Polygalae, Rhizoma Acori Tatarinowii and Poria. Historically, this decoction has three different formulations, each recorded at a different point in time. In this study, the chemical compositions of all three Kaixinsan formulae were analyzed. By using rapid resolution LC coupled with a diode-array detector and an ESI triple quadrupole tandem MS (QQQ-MS/MS), the Radix and Rhizome Ginseng-derived ginsenosides including Rb(1), Rd, Re, Rg(1), the Radix Polygalae-derived 3,6'-disinapoyl sucrose, the Rhizoma Acori Tatarinowii-derived alpha-and beta-asarone and the Poria-derived pachymic acid were compared among the three different formulations. The results showed variations in the solubility of different chemicals between one formula and the others. This systematic method developed could be used for the quality assessment of this herbal decoction. |
| 类目[WOS] | Chemistry, Analytical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | RADIX ASTRAGALI ; PC12 CELLS ; PERFORMANCE ; DX-9386 ; PRESCRIPTION ; PRINCIPLES ; SINENSIS ; EXTRACT ; GINSENG ; STRESS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000285312700007 |
| 公开日期 | 2015-08-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/23929]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Hong Kong Univ Sci & Technol, Div Life Sci, Sect Marine Ecol & Biotechnol, Hong Kong, Hong Kong, Peoples R China 2.Hong Kong Univ Sci & Technol, Ctr Chinese Med, Hong Kong, Hong Kong, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Kevin Y.,Fu, Q.,Xie, Heidi Q.,et al. Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae[J]. JOURNAL OF SEPARATION SCIENCE,2010,33(23-24):3666-3674. |
| APA | Zhu, Kevin Y..,Fu, Q..,Xie, Heidi Q..,Xu, Sherry L..,Cheung, Anna W. H..,...&Tsim, Karl W. K..(2010).Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae.JOURNAL OF SEPARATION SCIENCE,33(23-24),3666-3674. |
| MLA | Zhu, Kevin Y.,et al."Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae".JOURNAL OF SEPARATION SCIENCE 33.23-24(2010):3666-3674. |
入库方式： OAI收割
来源：昆明植物研究所
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