Cytotoxicity Study on Some Synthetic Aromatic Esters of 4 '-Demethyl-4-deoxypodophyllotoxin
文献类型：期刊论文
| 作者 | Wang, Juan-Juan1; Han, Hong-Jin2; Zeng, Guang-Zhi2; Xu, Hui1; Tan, Ning-Hua2 |
| 刊名 | LETTERS IN DRUG DESIGN & DISCOVERY
 |
| 出版日期 | 2011-11-01 |
| 卷号 | 8期号:9页码:857-860 |
| 关键词 | Aromatic ester Cytotoxicity Deoxypodophyllotoxin |
| 英文摘要 | To search for potential anti-cancer analogs, 16 aromatic esters of 4'-demethyl-4-deoxypodophyllotoxin ( 6a-p) were synthesized and tested their cytotoxicity on six cancer cell lines. The results indicated that all derivatives showed potent cytotoxic activity against A-549 cell line with IC50 values of 0.00009-0.037 mu g/mL. |
| 类目[WOS] | Chemistry, Medicinal |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | ANTITUMOR-ACTIVITY ; AGENTS ; DERIVATIVES ; ALKYL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000301480100010 |
| 公开日期 | 2015-08-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/23933]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.NW A&F Univ, Coll Sci, Lab Pharmaceut Design & Synth, Yangling 712100, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Juan-Juan,Han, Hong-Jin,Zeng, Guang-Zhi,et al. Cytotoxicity Study on Some Synthetic Aromatic Esters of 4 '-Demethyl-4-deoxypodophyllotoxin[J]. LETTERS IN DRUG DESIGN & DISCOVERY,2011,8(9):857-860. |
| APA | Wang, Juan-Juan,Han, Hong-Jin,Zeng, Guang-Zhi,Xu, Hui,&Tan, Ning-Hua.(2011).Cytotoxicity Study on Some Synthetic Aromatic Esters of 4 '-Demethyl-4-deoxypodophyllotoxin.LETTERS IN DRUG DESIGN & DISCOVERY,8(9),857-860. |
| MLA | Wang, Juan-Juan,et al."Cytotoxicity Study on Some Synthetic Aromatic Esters of 4 '-Demethyl-4-deoxypodophyllotoxin".LETTERS IN DRUG DESIGN & DISCOVERY 8.9(2011):857-860. |
入库方式： OAI收割
来源：昆明植物研究所
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