Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus
文献类型：期刊论文
| 作者 | Qiu, SX; Sun, HD ; Lobkovsky, E; Chai, H; Clardy, I; Farnsworth, NR; Pezzuto, JM; Fong, HHS
|
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 1998-12-01 |
| 卷号 | 64期号:8页码:728-731 |
| 关键词 | Isodon megathyrsus Labiatae leaves ent-kaurene diterpene human cancer lines cytotoxic activity 2D-NMR techniques X-ray crystallography megathyrin B electrospray LC/MS |
| 英文摘要 | From the leaves of Isodon megothyrsus, a novel entkaurene diterpene, megathyrin B, was isolated and its structure determined as 1 alpha,7 beta,11 beta,15 beta-tetrahydroxy-ent-7 alpha,20-epoxykaur-16-ene by 1D- and 2D-NMR spectral analysis. Additionally, its stereochemistry was unambiguously assigned by X-ray crystallography. This compound was cytotoxic to the KB and KB-V cell lines. |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000077915200010 |
| 公开日期 | 2015-08-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/23958]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA 2.Chinese Acad Sci, Kunming Inst Bot, Kunming, Peoples R China 3.Cornell Univ, Baker Lab, Dept Chem, Ithaca, NY 14853 USA |
| 推荐引用方式 GB/T 7714 | Qiu, SX,Sun, HD,Lobkovsky, E,et al. Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus[J]. PLANTA MEDICA,1998,64(8):728-731. |
| APA | Qiu, SX.,Sun, HD.,Lobkovsky, E.,Chai, H.,Clardy, I.,...&Fong, HHS.(1998).Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus.PLANTA MEDICA,64(8),728-731. |
| MLA | Qiu, SX,et al."Megathyrin B: A cytotoxic diterpene from Isodon megathyrsus".PLANTA MEDICA 64.8(1998):728-731. |
入库方式： OAI收割
来源：昆明植物研究所
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