Frequency-Dependent Escherichia coli Chemotaxis Behavior
文献类型：期刊论文
| 作者 | Zhu, Xuejun1,2; Si, Guangwei1,2; Deng, Nianpei2; Ouyang, Qi1,2; Wu, Tailin2; He, Zhuoran2; Jiang, Lili3 ; Luo, Chunxiong1,2; Tu, Yuhai2,4
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| 刊名 | PHYSICAL REVIEW LETTERS
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| 出版日期 | 2012-03-23 |
| 卷号 | 108期号:12 |
| ISSN号 | 0031-9007 |
| 产权排序 | 3 |
| 通讯作者 | Zhu, XJ (reprint author), Peking Univ, Ctr Microfluid & Nanotechnol, State Key Lab Artificial Microstruct & Mesoscop P, Sch Phys, Beijing 100871, Peoples R China. |
| 英文摘要 | We study Escherichia coli chemotaxis behavior in environments with spatially and temporally varying attractant sources by developing a unique microfluidic system. Our measurements reveal a frequency-dependent chemotaxis behavior. At low frequency, the E. coli population oscillates in synchrony with the attractant. In contrast, in fast-changing environments, the population response becomes smaller and out of phase with the attractant waveform. These observations are inconsistent with the well-known Keller-Segel chemotaxis equation. A new continuum model is proposed to describe the population level behavior of E. coli chemotaxis based on the underlying pathway dynamics. With the inclusion of a finite adaptation time and an attractant consumption rate, our model successfully explains the microfluidic experiments at different stimulus frequencies. |
| 学科主题 | Medical psychology |
| 收录类别 | SCI |
| 项目简介 | The authors would like to thank S. B. Liang and Y. H. Jin for discussions. This work is partially supported by the NSF of China (11021463, 11074009, 11174012), the MOST of China (2009CB918500), and the NFFTBS of China (J0630311). Y. T. is partially supported by a NIH grant (No. R01GM081747). |
| 原文出处 | http://scholar.harvard.edu/files/gsi/files/zhu-si-et_al._2012.pdf |
| 语种 | 英语 |
| WOS记录号 | WOS:000301854400011 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/12824]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Peking Univ, Ctr Microfluid & Nanotechnol, State Key Lab Artificial Microstruct & Mesoscop P, Sch Phys, Beijing 100871, Peoples R China 2.Peking Univ, Ctr Theoret Biol, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China 3.Chinese Acad Sci, Lab Funct Connectome & Dev, Key Lab Behav Sci, Inst Psychol, Beijing 100101, Peoples R China 4.IBM Corp, TJ Watson Res Ctr, Yorktown Hts, NY 10598 USA |
| 推荐引用方式 GB/T 7714 | Zhu, Xuejun,Si, Guangwei,Deng, Nianpei,et al. Frequency-Dependent Escherichia coli Chemotaxis Behavior[J]. PHYSICAL REVIEW LETTERS,2012,108(12). |
| APA | Zhu, Xuejun.,Si, Guangwei.,Deng, Nianpei.,Ouyang, Qi.,Wu, Tailin.,...&Tu, Yuhai.(2012).Frequency-Dependent Escherichia coli Chemotaxis Behavior.PHYSICAL REVIEW LETTERS,108(12). |
| MLA | Zhu, Xuejun,et al."Frequency-Dependent Escherichia coli Chemotaxis Behavior".PHYSICAL REVIEW LETTERS 108.12(2012). |
入库方式： OAI收割
来源：心理研究所
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