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Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes
文献类型:期刊论文
| 作者 | Lu, Ting; Sheng, Hongguang; Wu, Johnna; Cheng, Yuan ; Zhu, Jianming; Chen, Yan(陈雁)
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| 刊名 | NUTRITION RESEARCH
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| 出版日期 | 2012 |
| 卷号 | 32期号:6页码:408-412 |
| 关键词 | Cinnamon Type 2 diabetes Fasting blood glucose HbA(1c) Blood lipids Human |
| 英文摘要 | For thousands of years, cinnamon has been used as a traditional treatment in China. However, there are no studies to date that investigate whether cinnamon supplements are able to aid in the treatment of type 2 diabetes in Chinese subjects. We hypothesized cinnamon should be effective in improving blood glucose control in Chinese patients with type 2 diabetes. To address this hypothesis, we performed a randomized, double-blinded clinical study to analyze the effect of cinnamon extract on glycosylated hemoglobin A(1c) and fasting blood glucose levels in Chinese patients with type 2 diabetes. A total of 66 patients with type 2 diabetes were recruited and randomly divided into 3 groups: placebo and low-dose and high-dose supplementation with cinnamon extract at 120 and 360 mg/d, respectively. Patients in all 3 groups took gliclazide during the entire 3 months of the study. Both hemoglobin A(1c) and fasting blood glucose levels were significantly reduced in patients in the low- and high-dose groups, whereas they were not changed in the placebo group. The blood triglyceride levels were also significantly reduced in the low-dose group. The blood levels of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and liver transaminase remained unchanged in the 3 groups. In conclusion, our study indicates that cinnamon supplementation is able to significantly improve blood glucose control in Chinese patients with type 2 diabetes. (C) 2012 Elsevier Inc. All rights reserved. |
| 类目[WOS] | Nutrition & Dietetics |
| 关键词[WOS] | PLASMA-GLUCOSE ; LIPIDS ; PEOPLE ; TRIAL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000306392800003 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/69] ![]() |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_信号转导与营养相关疾病研究组 |
| 推荐引用方式 GB/T 7714 | Lu, Ting,Sheng, Hongguang,Wu, Johnna,et al. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes[J]. NUTRITION RESEARCH,2012,32(6):408-412. |
| APA | Lu, Ting,Sheng, Hongguang,Wu, Johnna,Cheng, Yuan,Zhu, Jianming,&Chen, Yan.(2012).Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes.NUTRITION RESEARCH,32(6),408-412. |
| MLA | Lu, Ting,et al."Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes".NUTRITION RESEARCH 32.6(2012):408-412. |
入库方式: OAI收割
来源:上海营养与健康研究所
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