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Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes

文献类型:期刊论文

作者Lu, Ting; Sheng, Hongguang; Wu, Johnna; Cheng, Yuan; Zhu, Jianming; Chen, Yan(陈雁)
刊名NUTRITION RESEARCH
出版日期2012
卷号32期号:6页码:408-412
关键词Cinnamon Type 2 diabetes Fasting blood glucose HbA(1c) Blood lipids Human
英文摘要For thousands of years, cinnamon has been used as a traditional treatment in China. However, there are no studies to date that investigate whether cinnamon supplements are able to aid in the treatment of type 2 diabetes in Chinese subjects. We hypothesized cinnamon should be effective in improving blood glucose control in Chinese patients with type 2 diabetes. To address this hypothesis, we performed a randomized, double-blinded clinical study to analyze the effect of cinnamon extract on glycosylated hemoglobin A(1c) and fasting blood glucose levels in Chinese patients with type 2 diabetes. A total of 66 patients with type 2 diabetes were recruited and randomly divided into 3 groups: placebo and low-dose and high-dose supplementation with cinnamon extract at 120 and 360 mg/d, respectively. Patients in all 3 groups took gliclazide during the entire 3 months of the study. Both hemoglobin A(1c) and fasting blood glucose levels were significantly reduced in patients in the low- and high-dose groups, whereas they were not changed in the placebo group. The blood triglyceride levels were also significantly reduced in the low-dose group. The blood levels of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and liver transaminase remained unchanged in the 3 groups. In conclusion, our study indicates that cinnamon supplementation is able to significantly improve blood glucose control in Chinese patients with type 2 diabetes. (C) 2012 Elsevier Inc. All rights reserved.
类目[WOS]Nutrition & Dietetics
关键词[WOS]PLASMA-GLUCOSE ; LIPIDS ; PEOPLE ; TRIAL
收录类别SCI
语种英语
WOS记录号WOS:000306392800003
版本出版稿
源URL[http://202.127.25.144/handle/331004/69]  
专题中国科学院上海生命科学研究院营养科学研究所_信号转导与营养相关疾病研究组
推荐引用方式
GB/T 7714
Lu, Ting,Sheng, Hongguang,Wu, Johnna,et al. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes[J]. NUTRITION RESEARCH,2012,32(6):408-412.
APA Lu, Ting,Sheng, Hongguang,Wu, Johnna,Cheng, Yuan,Zhu, Jianming,&Chen, Yan.(2012).Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes.NUTRITION RESEARCH,32(6),408-412.
MLA Lu, Ting,et al."Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes".NUTRITION RESEARCH 32.6(2012):408-412.

入库方式: OAI收割

来源:上海营养与健康研究所

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