Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation
文献类型：期刊论文
| 作者 | Yang, Ling; Wu, Ying; Li, Huaixin; Yu, Zhijie; Li, Xin; Liu, Yong（刘勇） ; Lin, Xu（林旭）; Chen, Yan（陈雁）
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| 刊名 | EUROPEAN JOURNAL OF HUMAN GENETICS
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| 出版日期 | 2008 |
| 卷号 | 16期号:6页码:759-761 |
| 关键词 | INSIG2 cross-sectional study obesity body weight Chinese population |
| 英文摘要 | Herbert et al reported association with obesity of a common DNA variant rs7566605 at 10 kb upstream of the INSIG2 gene. We analyzed rs7566605 polymorphism in 3125 Chinese in a cross-sectional study. We found no significant association of rs7566605 polymorphism with body mass index (BMI) and waist circumference among all participants (P = 0.52). However, if geographic location is considered, the C/C genotype of rs7566605 was marginally associated with increased levels of BMI and risk of obesity among individuals living in Shanghai (P = 0.06), indicating that the C/C genotype may contribute to obesity in certain subpopulation among Chinese under certain environmental settings. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Genetics & Heredity |
| 关键词[WOS] | OBESITY ; PROTEIN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000256113700014 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.144/handle/331004/95]  |
| 专题 | 中国科学院上海生命科学研究院营养科学研究所_信号转导与营养相关疾病研究组 中国科学院上海生命科学研究院营养科学研究所_人类营养与疾病研究组 中国科学院上海生命科学研究院营养科学研究所_糖脂代谢与调控研究组 |
| 推荐引用方式 GB/T 7714 | Yang, Ling,Wu, Ying,Li, Huaixin,et al. Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation[J]. EUROPEAN JOURNAL OF HUMAN GENETICS,2008,16(6):759-761. |
| APA | Yang, Ling.,Wu, Ying.,Li, Huaixin.,Yu, Zhijie.,Li, Xin.,...&Chen, Yan.(2008).Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation.EUROPEAN JOURNAL OF HUMAN GENETICS,16(6),759-761. |
| MLA | Yang, Ling,et al."Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation".EUROPEAN JOURNAL OF HUMAN GENETICS 16.6(2008):759-761. |
入库方式： OAI收割
来源：上海营养与健康研究所
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