The Role of MicroRNAs in Diabetic Nephropathy
文献类型：期刊论文
| 作者 | Wu, H; Kong, LL; Zhou, SS; Cui, WP; Xu, F; Luo, MY; Li, XQ; Tan, Y; Miao, LN |
| 刊名 | JOURNAL OF DIABETES RESEARCH
 |
| 出版日期 | 2014 |
| 期号 | 1页码:920134-920134 |
| 通讯作者 | Tan, Y (reprint author), Wenzhou Med Univ, Chinese Amer Res Inst Diabet Complicat, Wenzhou 325035, Peoples R China.,y0tan002@louisville.edu ; miaolining55@163.com |
| 英文摘要 | Diabetic nephropathy (DN), as one of the chronic complications of diabetes, is the major cause of end-stage renal disease. However, the pathogenesis of this disease is not fully understood. In recent years, research on microRNAs (miRNAs) has become a hotspot because of their critical role in regulating posttranscriptional levels of protein-coding genes that may serve as key pathogenic factors in diseases. Several miRNAs were found to participate in the pathogenesis of DN, while others showed renal protective effects. Therefore, targeting miRNAs that are involved in DN may have a good prospect in the treatment of the disease. The aim of this review is to summarize DN-related miRNAs and provide potential targets for diagnostic strategies and therapeutic intervention. |
| 学科主题 | Endocrinology & Metabolism; Research & Experimental Medicine |
| 类目[WOS] | Endocrinology & Metabolism ; Medicine, Research & Experimental |
| 关键词[WOS] | GROWTH-FACTOR-BETA ; NF-KAPPA-B ; INDUCED COLLAGEN EXPRESSION ; GLOMERULAR MESANGIAL CELLS ; PANCREATIC-CANCER CELLS ; RENAL FIBROSIS ; HEPATOCELLULAR-CARCINOMA ; KIDNEY-DISEASE ; UP-REGULATION ; SMALL RNAS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000341721400001 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/290]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Wu, H,Kong, LL,Zhou, SS,et al. The Role of MicroRNAs in Diabetic Nephropathy[J]. JOURNAL OF DIABETES RESEARCH,2014(1):920134-920134. |
| APA | Wu, H.,Kong, LL.,Zhou, SS.,Cui, WP.,Xu, F.,...&Miao, LN.(2014).The Role of MicroRNAs in Diabetic Nephropathy.JOURNAL OF DIABETES RESEARCH(1),920134-920134. |
| MLA | Wu, H,et al."The Role of MicroRNAs in Diabetic Nephropathy".JOURNAL OF DIABETES RESEARCH .1(2014):920134-920134. |
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