Life without A tail: New formats of long noncoding RNAs
文献类型：期刊论文
| 作者 | Zhang, Y; Yang, L; Chen, LL |
| 刊名 | INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
 |
| 出版日期 | 2014 |
| 卷号 | 54期号:1页码:338-349 |
| 关键词 | nonpolyadenylated RNAs MALAT1 NEAT1 sno-IncRNAs circular RNAs ciRNAs |
| 通讯作者 | Chen, LL (reprint author), Inst Biochem & Cell Biol, State Key Lab Mol Biol, Shanghai, Peoples R China.,linglingchen@sibcb.ac.cn |
| 英文摘要 | While most long noncoding RNAs (lncRNAs) appear indistinguishable from mRNAs, having 5' cap structures and 3' poly(A) tails, recent work has revealed new formats. Rather than taking advantage of the canonical cleavage and polyadenylation for their 3' end maturation, such lncRNAs are processed and stablized by a number of other mechanisms, including the RNase P cleavage to generate a mature 3' end, or capped by snoRNP complexes at both ends, or by forming circular structures. Importantly, such lncRNAs have also been implicated in gene expression regulation in mammalian cells. Here, we highlight recent progress in our understanding of the biogenesis and function of lncRNAs without a poly(A) tail. (C) 2013 Elsevier Ltd. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology; Cell Biology |
| 类目[WOS] | Biochemistry & Molecular Biology ; Cell Biology |
| 关键词[WOS] | SMALL NUCLEOLAR RNA ; PRADER-WILLI-SYNDROME ; NUCLEAR-BODIES ; GENE-EXPRESSION ; MESSENGER-RNAS ; CIRCULAR RNAS ; TRIPLE-HELIX ; SACCHAROMYCES-CEREVISIAE ; ALTERNATIVE CLEAVAGE ; MICRORNA SPONGES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000342524600036 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/295]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Zhang, Y,Yang, L,Chen, LL. Life without A tail: New formats of long noncoding RNAs[J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY,2014,54(1):338-349. |
| APA | Zhang, Y,Yang, L,&Chen, LL.(2014).Life without A tail: New formats of long noncoding RNAs.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY,54(1),338-349. |
| MLA | Zhang, Y,et al."Life without A tail: New formats of long noncoding RNAs".INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 54.1(2014):338-349. |
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