Human amniotic epithelial cells express specific markers of nerve cells and migrate along the nerve fibers in the corpus callosum
文献类型：期刊论文
| 作者 | Wu, ZY; Hu, GZ; Lu, Y; Liu, TJ; Huang, Q; Guo, LH |
| 刊名 | NEURAL REGENERATION RESEARCH
 |
| 出版日期 | 2012 |
| 卷号 | 7期号:1页码:41-45 |
| 关键词 | human amniotic epithelial cells cell transplantation microtubule-associated protein-2 glial fibrillary acidic protein nestin neurotrophin central nervous system injury neural regeneration |
| 通讯作者 | Hu, GZ (reprint author), Soochow Univ, Dept Neurosurg, Affiliated Hosp 1, Suzhou 215006, Jiangsu, Peoples R China.,guozhen-hui@163.com ; lhguo@sibs.ac.cn |
| 英文摘要 | Human amniotic epithelial cells were isolated from a piece of fresh amnion. Using immunocytochemical methods, we investigated the expression of neuronal phenotypes (microtubule-associated protein-2, glial fibrillary acidic protein and nestin) in human amniotic epithelial cells. The conditioned medium of human amniotic epithelial cells promoted the growth and proliferation of rat glial cells cultured in vitro, and this effect was dose-dependent. Human amniotic epithelial cells were further transplanted into the corpus striatum of healthy adult rats and the grafted cells could integrate with the host and migrate 1-2 mm along the nerve fibers in corpus callosum. Our experimental findings indicate that human amniotic epithelial cells may be a new kind of seed cells for use in neurograft. |
| 学科主题 | Cell Biology; Neurosciences & Neurology |
| 类目[WOS] | Cell Biology ; Neurosciences |
| 关键词[WOS] | NEURAL STEM-CELLS ; TRANSPLANTATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000299915000008 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/534]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Wu, ZY,Hu, GZ,Lu, Y,et al. Human amniotic epithelial cells express specific markers of nerve cells and migrate along the nerve fibers in the corpus callosum[J]. NEURAL REGENERATION RESEARCH,2012,7(1):41-45. |
| APA | Wu, ZY,Hu, GZ,Lu, Y,Liu, TJ,Huang, Q,&Guo, LH.(2012).Human amniotic epithelial cells express specific markers of nerve cells and migrate along the nerve fibers in the corpus callosum.NEURAL REGENERATION RESEARCH,7(1),41-45. |
| MLA | Wu, ZY,et al."Human amniotic epithelial cells express specific markers of nerve cells and migrate along the nerve fibers in the corpus callosum".NEURAL REGENERATION RESEARCH 7.1(2012):41-45. |
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