Viral proteins function as ion channels
文献类型：期刊论文
| 作者 | Wang, K; Xie, SQ; Sun, B |
| 刊名 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
 |
| 出版日期 | 2011 |
| 卷号 | 1808期号:2页码:510-515 |
| 关键词 | Viral ion channels PBCV-1 Influenza HIV-1 HCV Picornavirus Coronavirus |
| 通讯作者 | Sun, B (reprint author), Chinese Acad Sci, Inst Pasteur Shanghai, Shanghai Inst Biol Sci, Mol Virol Lab, 411 He Fei Rd, Shanghai 200025, Peoples R China.,bsun@sibs.ac.cn |
| 英文摘要 | Viral ion channels are short membrane proteins with 50-120 amino acids and play an important role either in regulating virus replication, such as virus entry, assembly and release or modulating the electrochemical balance in the subcellular compartments of host cells. This review summarizes the recent advances in viral encoded ion channel proteins (or viroporins), including PBCV-1 KcV, influenza M2, HIV-1 Vpu, HCV p7, picornavirus 2B, and coronavirus E and 3a. We focus on their function and mechanisms, and also discuss viral ion channel protein serving as a potential drug target. (C) 2010 Elsevier B.V. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | HEPATITIS-C-VIRUS ; INFLUENZA-A VIRUS ; CORONAVIRUS ENVELOPE PROTEIN ; COXSACKIEVIRUS 2B PROTEIN ; INTEGRAL MEMBRANE GLYCOPROTEIN ; MODULATING CYCLOPHILIN LIGAND ; ESCHERICHIA-COLI-CELLS ; M-2 PROTON CHANNEL ; VPU PROTEIN ; M2 PROTEIN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000286681700002 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/748]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Wang, K,Xie, SQ,Sun, B. Viral proteins function as ion channels[J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES,2011,1808(2):510-515. |
| APA | Wang, K,Xie, SQ,&Sun, B.(2011).Viral proteins function as ion channels.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES,1808(2),510-515. |
| MLA | Wang, K,et al."Viral proteins function as ion channels".BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1808.2(2011):510-515. |
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