Members of miR-169 family are induced by high salinity and transiently inhibit the NF-YA transcription factor
文献类型：期刊论文
| 作者 | Zhao, BT; Ge, LF; Liang, RQ; Li, W; Ruan, KC; Lin, HX; Jin, YX |
| 刊名 | BMC MOLECULAR BIOLOGY
 |
| 出版日期 | 2009 |
| 卷号 | 10期号:1页码:29-29 |
| 通讯作者 | Jin, YX (reprint author), Chinese Acad Sci, State Key Lab Mol Biol, Inst Biochem & Cell Biol, Shanghai Inst Biol Sci, Shanghai 200031, Peoples R China.,botaozhao@gmail.com ; jxshun@gmail.com ; Ruqiang.Liang@gmail.com ; tulip_lw@hotmail.com ; kcruan@sibs.ac.cn ; hxlin@sippe.ac.cn ; yxjin@sibs.ac.cn |
| 英文摘要 | Background: MicroRNAs (miRNAs) are endogenously expressed small RNAs with a length of about 21 nt. MiRNAs silence their target genes at the post-transcriptional level. In plants, miRNAs play various developmental and physiological roles by cleavaging mRNAs predominantly. Drought and high salinity are the most severe environmental abiotic stresses and cause crop losses all over the world. Results: In this study, we identified miR-169g and miR-169n (o) as high salinity-responsive miRNAs in rice. MiR-169n and miR169o were in a miRNA cluster with a distance of 3707 base pairs (bp). The high degree of conservation and close phylogenic distance of pre-miR-169n and pre-miR-169o indicated that they were derived from a very recent tandem duplication evolutionary event. The existence of a cis-acting abscisic acid responsive element (ABRE) in the upstream region of miR-169n (o) suggested that miR-169n (o) may be regulated by ABA. In our previous study, we found that miR-169g was induced by the osmotic stress caused by drought via a dehydration-responsive element (DRE). Thus, our data showed that there were both overlapping and distinct responses of the miR-169 family to drought and salt stresses. We also showed that these miR-169 members selectively cleaved one of the NF-YA genes, Os03g29760, which is a CCAAT-box binding transcription factor and participates in transcriptional regulation of large number genes. Finally, we found one or more ath-miR-169 member that was also induced by high salinity. Conclusion: We identified members of the miR-169 family as salt-induced miRNAs and analyzed their evolution, gene organization, expression, transcriptional regulation motif and target gene. Our data also indicated that the salt-induction of some miR-169 members was a general property in plants. |
| 学科主题 | Biochemistry & Molecular Biology |
| 类目[WOS] | Biochemistry & Molecular Biology |
| 关键词[WOS] | ARABIDOPSIS-THALIANA ; EXPRESSION PROFILES ; CDNA MICROARRAY ; PLANT MICRORNA ; REGULATORY NETWORKS ; GENE-EXPRESSION ; STRESS-RESPONSE ; NUCLEAR EXPORT ; SALT STRESS ; RICE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000265849700001 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/1308]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Zhao, BT,Ge, LF,Liang, RQ,et al. Members of miR-169 family are induced by high salinity and transiently inhibit the NF-YA transcription factor[J]. BMC MOLECULAR BIOLOGY,2009,10(1):29-29. |
| APA | Zhao, BT.,Ge, LF.,Liang, RQ.,Li, W.,Ruan, KC.,...&Jin, YX.(2009).Members of miR-169 family are induced by high salinity and transiently inhibit the NF-YA transcription factor.BMC MOLECULAR BIOLOGY,10(1),29-29. |
| MLA | Zhao, BT,et al."Members of miR-169 family are induced by high salinity and transiently inhibit the NF-YA transcription factor".BMC MOLECULAR BIOLOGY 10.1(2009):29-29. |
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