Biological characteristics of dengue virus and potential targets for drug design
文献类型：期刊论文
| 作者 | Qi, RF; Zhang, L; Chi, CW |
| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
 |
| 出版日期 | 2008 |
| 卷号 | 40期号:2页码:91-101 |
| 关键词 | dengue virus NS3 protease polyprotein processing drug target |
| 通讯作者 | Chi, CW (reprint author), Tongji Univ, Inst Prot Res, Shanghai 200092, Peoples R China.,zwqi@sibs.ac.cn |
| 英文摘要 | Dengue infection is a major cause of morbidity in tropical and subtropical regions, bringing nearly 40% of the world population at risk and causing more than 20,000 deaths per year. But there is neither a vaccine for dengue disease nor antiviral drugs to treat the infection. In recent years, dengue infection has been particularly prevalent in India, Southeast Asia, Brazil, and Guangdong Province, China. In this article, we present a brief summary of the biological characteristics of dengue virus and associated flaviviruses, and outline the progress on studies of vaccines and drugs based on potential targets of the dengue virus. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | BORNE ENCEPHALITIS-VIRUS ; DEPENDENT RNA-POLYMERASE ; YELLOW-FEVER VIRUS ; WEST-NILE-VIRUS ; STIMULATED NUCLEOSIDE TRIPHOSPHATASE ; FLAVIVIRUS ENVELOPE GLYCOPROTEIN ; NONSTRUCTURAL PROTEIN NS3 ; RETRACTED ARTICLE. SEE ; IN-VITRO ; MONOCLONAL-ANTIBODIES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000253501900001 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/1335]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Qi, RF,Zhang, L,Chi, CW. Biological characteristics of dengue virus and potential targets for drug design[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2008,40(2):91-101. |
| APA | Qi, RF,Zhang, L,&Chi, CW.(2008).Biological characteristics of dengue virus and potential targets for drug design.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,40(2),91-101. |
| MLA | Qi, RF,et al."Biological characteristics of dengue virus and potential targets for drug design".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 40.2(2008):91-101. |
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