Epidermal growth factor induces changes of interaction between epidermal growth factor receptor and actin in intact cells
文献类型：期刊论文
| 作者 | Song, W; Xuan, HX; Lin, QS |
| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
 |
| 出版日期 | 2008 |
| 卷号 | 40期号:8页码:754-760 |
| 关键词 | epidermal growth factor receptor actin fluorescence resonance energy transfer interaction |
| 通讯作者 | Lin, QS (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Mol Cell Biol, Shanghai 200031, Peoples R China.,qslin@sibs.ac.cn |
| 英文摘要 | The epidermal growth factor receptor (EGFR) is a cyto-skeleton-binding protein. Although purified EGFR can interact with acting in vitro and normally at least 10% of EGFR exist in the insoluble cytoskeleton fraction of A431 cells, interaction of cytosolic EGFR with actin can only be visualized by fluorescence resonance energy transfer when epidermal growth factor presents in the cell medium. Results indicate that the correct orientation between EGFR and actin is important in the signal transduction process. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | TYROSINE KINASE-ACTIVITY ; EGF RECEPTOR ; CYTOSKELETON ; PROTEIN ; BINDING ; INTERNALIZATION ; POLYMERIZATION ; PROLIFERATION ; STIMULATION ; ENDOCYTOSIS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000258375800009 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/1412]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Song, W,Xuan, HX,Lin, QS. Epidermal growth factor induces changes of interaction between epidermal growth factor receptor and actin in intact cells[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2008,40(8):754-760. |
| APA | Song, W,Xuan, HX,&Lin, QS.(2008).Epidermal growth factor induces changes of interaction between epidermal growth factor receptor and actin in intact cells.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,40(8),754-760. |
| MLA | Song, W,et al."Epidermal growth factor induces changes of interaction between epidermal growth factor receptor and actin in intact cells".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 40.8(2008):754-760. |
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