Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter
文献类型：期刊论文
| 作者 | Gao, DM; Wang, LF; Liu, J; Kong, YY; Wang, YA; Xie, YH |
| 刊名 | FEBS LETTERS
 |
| 出版日期 | 2006 |
| 卷号 | 580期号:7页码:1702-1708 |
| 关键词 | mLRH-1 transcript promoter embryogenesis |
| 通讯作者 | Xie, YH (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, State Key Lab Mol Biol, S212,Yueyang Rd 320, Shanghai 200031, Peoples R China.,yhxie@sibs.ac.cn |
| 英文摘要 | Liver receptor homologue 1 (LRH-1) plays important roles in many physiological processes and embryogenesis. However, little is known about the developmental regulation of lrh-1 expression. We identified a novel transcript of mouse lrh-1 (mlrh-1v2) from embryonic stem (ES) cells. mlrh-1v2 is expressed throughout embryogenesis and in several adult tissues, while the known transcript (mlrh-1v1) appears later during embryogenesis. mlrh-1v2 expression is directed by a new promoter which displays a strong activity in ES cells. The generation of the new transcript is conserved in rats. The identification of novel mlrh-1 variant and promoter is critical for elucidating LRH-1 functions in development and adult tissues. (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology ; Biophysics ; Cell Biology |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics ; Cell Biology |
| 关键词[WOS] | LIVER RECEPTOR HOMOLOG-1 ; FETOPROTEIN TRANSCRIPTION FACTOR ; ORPHAN NUCLEAR RECEPTOR ; FACTOR FTF GENE ; REGULATES EXPRESSION ; LRH-1 ; AROMATASE ; PANCREAS ; HB1F |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000236338300002 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/1745]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Gao, DM,Wang, LF,Liu, J,et al. Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter[J]. FEBS LETTERS,2006,580(7):1702-1708. |
| APA | Gao, DM,Wang, LF,Liu, J,Kong, YY,Wang, YA,&Xie, YH.(2006).Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter.FEBS LETTERS,580(7),1702-1708. |
| MLA | Gao, DM,et al."Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter".FEBS LETTERS 580.7(2006):1702-1708. |
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