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Ubiquitin-like protein ISG15 and its role in innate immunity

文献类型：期刊论文

作者Liu, C; Qiao, WT; Wang, C; Geng, YQ
刊名PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
出版日期2006
卷号33期号:11页码:1023-1029
关键词ISG15 ubiquitin-like modification innate immunity interferon regulation
通讯作者Geng, YQ (reprint author), Nankai Univ, Coll Life Sci, Tianjin 300071, Peoples R China.,gengyq@nankai.edu.cn
英文摘要Virus infection or interferon can stimulate robust expression of the protein ISG15 that is encoded by interferon stimulated gene 15, which was the first unbiquitin-like molecule identified two decades ago. While ubiquitin and its many important functions have been well established, the functions of ISG15 and its post-translational conjugation are still largely unknown. Recently, some specific enzymes have been identified to be involved in the ISG15 modification system, suggests that ISG15 and its modification system play important roles in the innate immune response and regulation of interferon signaling. The history of ISG15 discovery and its biochemical characterization were briefly introduced. Then such topics as the ISG15 gene expression and the ISG15 modification will be focued on, and finally summarize new findings which have implications for ISG15 and its modification system in immunology and interferon signal transduction were summarized.
学科主题Biochemistry & Molecular Biology; Biophysics
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]INDUCED 15-KDA PROTEIN ; UBP43 USP18 ; INTERFERON ; CELLS ; GENE ; ENZYME ; TRANSCRIPTION ; CONJUGATION ; ISGYLATION ; SEQUENCE
收录类别SCI
语种中文
WOS记录号WOS:000242141700001
版本出版稿
源URL[http://202.127.25.143/handle/331003/1775]  
专题上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式
GB/T 7714		 Liu, C,Qiao, WT,Wang, C,et al. Ubiquitin-like protein ISG15 and its role in innate immunity[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2006,33(11):1023-1029.
APA Liu, C,Qiao, WT,Wang, C,&Geng, YQ.(2006).Ubiquitin-like protein ISG15 and its role in innate immunity.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,33(11),1023-1029.
MLA Liu, C,et al."Ubiquitin-like protein ISG15 and its role in innate immunity".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 33.11(2006):1023-1029.

入库方式： OAI收割

来源：上海生物化学与细胞生物学研究所

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