Complete genome sequence and biological characterizations of a novel goose paramyxovirus-SF02 isolated in China
文献类型:期刊论文
作者 | Zou, J; Shan, SH; Yao, NT; Gong, ZX |
刊名 | VIRUS GENES
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出版日期 | 2005 |
卷号 | 30期号:1页码:13-21 |
关键词 | APMV-1 (NDV) biological characterization genomic sequence pathogenicity phylogenetic SF02 |
通讯作者 | Gong, ZX (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Prote, Shanghai 200031, Peoples R China.,gongzx@sunm.shcnc.ac.cn |
英文摘要 | A Paramyxovirus designated as APMV-1 (NDV) Isolate SF02 (abbre. as SF02) was recently isolated from goose in China. SF02 was identified as a member of Newcastle disease virus (NDV) genotype VII. NDV strains are generally pathogenic only for fowls, including chicken and pigeon, and not for waterfowls such as goose and duck, whereas SF02 is highly pathogenic for both fowls and waterfowls. In the present study the complete genome consisting of 15, 192 nucleotides of SF02 was sequenced. Genomes of SF02 and all known APMV-1, Strains contain 6 ORFs in the order of NP-P-M-F-HN-L, and that of SF02 had an extra 6 nts between NP and P genes. Moreover, an anti-sense ORF consisting of 549 nt at the 1960 to 1412 and deduced 182 amino acids was found in SF02. The SF02 genome shared 83% identity and its 6 ORFs 81.9-86.1% identities with the reference APMV-I strains. The possible mechanism determining different host range and pathogenicity is discussed based on genetic analyses. |
学科主题 | Genetics & Heredity; Virology |
类目[WOS] | Genetics & Heredity ; Virology |
关键词[WOS] | NEWCASTLE-DISEASE-VIRUS ; COMPLETE NUCLEOTIDE-SEQUENCE ; NUCLEOCAPSID PROTEIN GENE ; V-PROTEIN ; PHYLOGENETIC-RELATIONSHIPS ; FUSION PROTEIN ; SENDAI-VIRUS ; OUTBREAKS ; INTERFERON ; VIRULENT |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000227012600002 |
版本 | 出版稿 |
源URL | [http://202.127.25.143/handle/331003/1851] ![]() |
专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
推荐引用方式 GB/T 7714 | Zou, J,Shan, SH,Yao, NT,et al. Complete genome sequence and biological characterizations of a novel goose paramyxovirus-SF02 isolated in China[J]. VIRUS GENES,2005,30(1):13-21. |
APA | Zou, J,Shan, SH,Yao, NT,&Gong, ZX.(2005).Complete genome sequence and biological characterizations of a novel goose paramyxovirus-SF02 isolated in China.VIRUS GENES,30(1),13-21. |
MLA | Zou, J,et al."Complete genome sequence and biological characterizations of a novel goose paramyxovirus-SF02 isolated in China".VIRUS GENES 30.1(2005):13-21. |
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