Regulation of the expression of histone H3.3 by differential polyadenylation
文献类型：期刊论文
| 作者 | Feng, RR; Tang, XY; Becker, A; Berger, A; Ye, J; Akhmanova, A; Hennig, W |
| 刊名 | GENOME
 |
| 出版日期 | 2005 |
| 卷号 | 48期号:3页码:503-510 |
| 关键词 | histone H3.3 polyadenylation oogenesis spermatogenesis histone translation |
| 通讯作者 | Hennig, W (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, DAAD lab, 320 Yue Yang Rd, Shanghai 200031, Peoples R China.,whennig@gmx.de |
| 英文摘要 | Previously we have shown that the 3' untranslated regions (UTRs) of the replacement histone genes H3.3.A and H3.3B of Drosophila melanogaster differ in their nucleotide sequences and have different polyadenylation sites. To understand their functional relevance, which might explain the presence and evolutionary conservation of 2 different H3.3 genes, green flourescent protein (GFP) constructs with different 3' UTR sections were studied by the expression of GFP as a marker protein. Here we show that the polyadenylation signals modify the cell-specific translation of the histone replacement variants in testes and ovaries. The H3.3A gene may be required to provide postmeiotic histone H3.3 in the male germ line in transition to chromatin packaging in sperm. |
| 学科主题 | Biotechnology & Applied Microbiology; Genetics & Heredity |
| 类目[WOS] | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 关键词[WOS] | DROSOPHILA-MELANOGASTER ; CHROMOSOMAL-PROTEINS ; CHROMATIN ; GENES ; VARIANTS ; SPECIFY ; SPERM ; HYDEI |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000230818900014 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/1880]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Feng, RR,Tang, XY,Becker, A,et al. Regulation of the expression of histone H3.3 by differential polyadenylation[J]. GENOME,2005,48(3):503-510. |
| APA | Feng, RR.,Tang, XY.,Becker, A.,Berger, A.,Ye, J.,...&Hennig, W.(2005).Regulation of the expression of histone H3.3 by differential polyadenylation.GENOME,48(3),503-510. |
| MLA | Feng, RR,et al."Regulation of the expression of histone H3.3 by differential polyadenylation".GENOME 48.3(2005):503-510. |
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