Pyrrolysine: The 22nd amino acid
文献类型:期刊论文
作者 | Ling, C; Wang, ED |
刊名 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
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出版日期 | 2005 |
卷号 | 32期号:6页码:490-494 |
关键词 | pyrrolysine tRNA(Pyl) pyrrolysyl-tRNA synthetase pyrrolysine inserting element selenocysteine |
通讯作者 | Wang, ED (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Mol Biol, Inst Biochem & Cell Biol, Shanghai 200031, Peoples R China.,edwang@sibs.ac.cn |
英文摘要 | Pyrrolysine, known as the 22nd amino acid, is found in Methanosarcina barkeri (M. barkeri) methylamine methyltransferases. It comes from the sense decoding of the UAG amber stop codon. It has specific pyrrolysyl-tRNA synthetase and tRNA(Pyl). tRNA(Pyl) has noncanonical secondary structure. M. barkeri has two routes: direct and indirect routes to synthesize pyrrolysyl-tRNA(Pyl). The special structure in the mRNA and other unknown mechanisms may control the decoding of UAG as pyrrolysine or termination signal. Pyrrolysine was compared with the 21st amino acid: selenocysteine. |
学科主题 | Biochemistry & Molecular Biology; Biophysics |
类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
关键词[WOS] | TRANSFER-RNA SYNTHESIS ; METHANOSARCINA-BARKERI ; METHYLTRANSFERASE ; ARCHAEA ; GENE ; MONOMETHYLAMINE ; GENOME ; UAG |
收录类别 | SCI |
语种 | 中文 |
WOS记录号 | WOS:000230057000002 |
版本 | 出版稿 |
源URL | [http://202.127.25.143/handle/331003/1928] ![]() |
专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
推荐引用方式 GB/T 7714 | Ling, C,Wang, ED. Pyrrolysine: The 22nd amino acid[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2005,32(6):490-494. |
APA | Ling, C,&Wang, ED.(2005).Pyrrolysine: The 22nd amino acid.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,32(6),490-494. |
MLA | Ling, C,et al."Pyrrolysine: The 22nd amino acid".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 32.6(2005):490-494. |
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