Comparative study of interaction of two type II ribosome-inactivating proteins and their A-chains with model membrane
文献类型：期刊论文
| 作者 | Xu, H; Wang, BZ; Liu, WY |
| 刊名 | PROTEIN AND PEPTIDE LETTERS
 |
| 出版日期 | 2004 |
| 卷号 | 11期号:2页码:157-163 |
| 关键词 | aggregation cinnamomin leakage membrane pH-dependence ricin |
| 通讯作者 | Liu, WY (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, State Key Lab Mol Biol, 320 Yueyang Rd, Shanghai, Peoples R China.,wyliu@sibs.ac.cn |
| 英文摘要 | Both cinnamomin and ricin are type 11 ribosome-inactivating proteins. Cinnamomin is less cytotoxic compared with ricin. In order to clarify the mechanism of their different cytotoxicities, the interaction of cinnamomin and its A-chain with model membrane was investigated and compared with that of ricin and its A-chain. It was revealed that cinnamomin is less effective than ricin in interacting with model membrane. Cinnamomin A-chain interacts with model membrane much less violently than ricin A-chain. The differences in the interaction of cinnamomin, ricin or their A-chains with model membrane might at least in part indicate the different cytotoxicity between cinnamomin and ricin. |
| 学科主题 | Biochemistry & Molecular Biology |
| 类目[WOS] | Biochemistry & Molecular Biology |
| 关键词[WOS] | SAMBUCUS-NIGRA ; CELL-LINES ; RICIN ; TRANSLOCATION ; CINNAMOMIN ; CYTOTOXICITY ; TOXICITY ; EBULIN-1 ; PEPTIDE ; BINDING |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000220649600007 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2035]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Xu, H,Wang, BZ,Liu, WY. Comparative study of interaction of two type II ribosome-inactivating proteins and their A-chains with model membrane[J]. PROTEIN AND PEPTIDE LETTERS,2004,11(2):157-163. |
| APA | Xu, H,Wang, BZ,&Liu, WY.(2004).Comparative study of interaction of two type II ribosome-inactivating proteins and their A-chains with model membrane.PROTEIN AND PEPTIDE LETTERS,11(2),157-163. |
| MLA | Xu, H,et al."Comparative study of interaction of two type II ribosome-inactivating proteins and their A-chains with model membrane".PROTEIN AND PEPTIDE LETTERS 11.2(2004):157-163. |
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