Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis
文献类型：期刊论文
| 作者 | Wang, SL; He, Y; Xie, YH; Wang, Y; Li, JZ; Wang, L; Wang, ZG; Fu, JL |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2004 |
| 卷号 | 49期号:2页码:142-145 |
| 关键词 | human B1 binding factor (hB1F) transgenic mouse lineage establishment phenotype analysis |
| 通讯作者 | Fu, JL (reprint author), Second Mil Med Univ, Dept Med Genet, Shanghai 200433, Peoples R China.,jlfu@guomai.sh.cn |
| 英文摘要 | Human nuclear receptor hB1F is a novel member of the fushi tarazu factor I subfamily of nuclear receptor superfamily. The studies about its homologous genes indicate that hB1F may play a key role in regulating the metabolic homeostasis of cholesterol. After obtaining the founder mice carrying the transgene of hb1f by microinjection, each founder was mated to normal C57 mouse and the positive F1 by PCR identification of the same founder were intercrossed within sisters and brothers to establish the transgenic mouse lineage. The results of F1, F2 and offspring of test cross identification showed that the widely expressed hb1f transgenic mouse lineage was established successfully in this study. The tissue morphology of the transgenic lineage was also analyzed preliminarily. |
| 学科主题 | Science & Technology - Other Topics |
| 类目[WOS] | Multidisciplinary Sciences |
| 关键词[WOS] | HEPATITIS-B-VIRUS ; FETOPROTEIN TRANSCRIPTION FACTOR ; ORPHAN NUCLEAR RECEPTOR ; ACID SYNTHESIS ; ENHANCER II ; GENE ; PROMOTER ; INTESTINE ; MICE ; FTF |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000220239800007 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2048]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Wang, SL,He, Y,Xie, YH,et al. Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis[J]. CHINESE SCIENCE BULLETIN,2004,49(2):142-145. |
| APA | Wang, SL.,He, Y.,Xie, YH.,Wang, Y.,Li, JZ.,...&Fu, JL.(2004).Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis.CHINESE SCIENCE BULLETIN,49(2),142-145. |
| MLA | Wang, SL,et al."Establishment of widely expressed hb1f transgenic mouse lineage and its morphologic analysis".CHINESE SCIENCE BULLETIN 49.2(2004):142-145. |
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