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Cinnamomin - a versatile type II ribosome-inactivating protein

文献类型：期刊论文

作者Xu, H; Liu, WY
刊名ACTA BIOCHIMICA ET BIOPHYSICA SINICA
出版日期2004
卷号36期号:3页码:169-176
关键词cinnamonin cinphorin ribosome-inactivating protein
通讯作者Liu, WY (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, State Key Lab Mol Biol, 320 Yueyang Rd, Shanghai 200031, Peoples R China.,wyliu@sibs.ac.cn
英文摘要Ribosome-inactivating proteins (RIPs) are a group of toxic proteins that can specifically act on the universally conserved sarcin/ricin domain (S/R domain) of the largest RNA in ribosome and thus irreversibly inactivate ribosome for protein synthesis. Cinnamomin is a multifunctional type 11 RIP isolated in our laboratory from the mature seeds of the camphor tree. This protein has been extensively studied with regard to its purification, characteristics, structure and function, genetic expression, enzymatic mechanism, physiological role in seed cell and toxicity to cancer cells and insect larvae. The research results of cinnamomin obtained in our laboratory are summarized in this review. Understanding of cinnamomin and the relative new proteins will help expand our knowledge of RIPs and may accelerate theoretical study and the development of their potential applications.
学科主题Biochemistry & Molecular Biology; Biophysics
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]N-GLYCOSIDASE ACTIVITY ; DOUBLE-STRANDED DNA ; RICIN A-CHAIN ; CAMPHOR TREE ; SIMULTANEOUS EXISTENCE ; EUKARYOTIC RIBOSOMES ; TOXIC PROTEIN ; MATURE SEEDS ; B-CHAIN ; RNA
收录类别SCI
语种英语
WOS记录号WOS:000221073900001
版本出版稿
源URL[http://202.127.25.143/handle/331003/2056]  
专题上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式
GB/T 7714		 Xu, H,Liu, WY. Cinnamomin - a versatile type II ribosome-inactivating protein[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2004,36(3):169-176.
APA Xu, H,&Liu, WY.(2004).Cinnamomin - a versatile type II ribosome-inactivating protein.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,36(3),169-176.
MLA Xu, H,et al."Cinnamomin - a versatile type II ribosome-inactivating protein".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 36.3(2004):169-176.

入库方式： OAI收割

来源：上海生物化学与细胞生物学研究所

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