Activin/Nodal signals mediate the ventral expression of myf-5 in Xenopus gastrula embryos
文献类型：期刊论文
| 作者 | Chen, Y; Lin, GF; Hu, RY; Chen, YG; Ding, XY |
| 刊名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
 |
| 出版日期 | 2003 |
| 卷号 | 310期号:1页码:121-127 |
| 关键词 | Activin/Nodal signals Smad binding element Xenopus myf-5 myogenesis |
| 通讯作者 | Ding, XY (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Lab Mol & Cell Biol,Lab Stem Cell Biol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China., |
| 英文摘要 | Expression of myf-5, a key component of myogenic regulatory genes, expands into the ventral marginal zone during Xenopus gastrulation after the dorsal activation takes place. Little is known about how this dynamic expression pattern occurs. Here, we provide evidences to suggest that Activin/Nodal signals participate in the regulation of ventral expression of Xmyf-5 in gastrula embryos. Two Smad binding elements (SBEs) within the Xenopus myf-5 promoter can specifically interact with Smad4 protein. Furthermore, we demonstrate that the two SBEs are both indispensable for conferring responsiveness to Activin/Nodal signals and to ventral expression of myf-5 in Xenopus gastrula embryos. (C) 2003 Elsevier Inc. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology ; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | NODAL-RELATED SIGNALS ; VERTEBRATE EMBRYOS ; MESODERM INDUCTION ; SPEMANNS ORGANIZER ; SPECIFICATION ; ESTABLISHMENT ; BINDING ; LAEVIS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000185835500020 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2214]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Chen, Y,Lin, GF,Hu, RY,et al. Activin/Nodal signals mediate the ventral expression of myf-5 in Xenopus gastrula embryos[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2003,310(1):121-127. |
| APA | Chen, Y,Lin, GF,Hu, RY,Chen, YG,&Ding, XY.(2003).Activin/Nodal signals mediate the ventral expression of myf-5 in Xenopus gastrula embryos.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,310(1),121-127. |
| MLA | Chen, Y,et al."Activin/Nodal signals mediate the ventral expression of myf-5 in Xenopus gastrula embryos".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 310.1(2003):121-127. |
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