T-box binding site mediates the dorsal activation of myf-5 in Xenopus gastrula embryos
文献类型：期刊论文
| 作者 | Lin, GF; Geng, X; Chen, Y; Qu, B; Wang, FB; Hu, RY; Ding, XY |
| 刊名 | DEVELOPMENTAL DYNAMICS
 |
| 出版日期 | 2003 |
| 卷号 | 226期号:1页码:51-58 |
| 关键词 | Xenopus myogenesis myf-5 T-box binding site restriction enzyme mediated integration transgenesis |
| 通讯作者 | Ding, XY (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China.,xyding@sunm.shcnc.ac.cn |
| 英文摘要 | Myf-5, a member of the muscle regulatory factor family of transcription factors, plays an important role in the determination, development, and differentiation of the skeletal muscle. Factors that regulate the expression of myf-5 itself are not well understood. We show here that a T-box binding site in the Xenopus myf-5 promoter mediated the activation of myf-5 expression through specific interaction with nuclear proteins of gastrula embryos. The T-box binding site could be bound by and respond to T-box proteins. T-box genes could induce Xmyf-5. The results suggest that T-box proteins are involved in the specification of myogenic mesoderm and muscle development. |
| 学科主题 | Anatomy & Morphology; Developmental Biology |
| 类目[WOS] | Anatomy & Morphology ; Developmental Biology |
| 关键词[WOS] | MESODERM INDUCTION ; MUSCLE DETERMINATION ; MATERNAL VEGT ; EXPRESSION ; GENE ; MYOGENESIS ; CELLS ; DIFFERENTIATION ; BRACHYURY ; MORPHOGEN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000180245900007 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2236]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Lin, GF,Geng, X,Chen, Y,et al. T-box binding site mediates the dorsal activation of myf-5 in Xenopus gastrula embryos[J]. DEVELOPMENTAL DYNAMICS,2003,226(1):51-58. |
| APA | Lin, GF.,Geng, X.,Chen, Y.,Qu, B.,Wang, FB.,...&Ding, XY.(2003).T-box binding site mediates the dorsal activation of myf-5 in Xenopus gastrula embryos.DEVELOPMENTAL DYNAMICS,226(1),51-58. |
| MLA | Lin, GF,et al."T-box binding site mediates the dorsal activation of myf-5 in Xenopus gastrula embryos".DEVELOPMENTAL DYNAMICS 226.1(2003):51-58. |
入库方式： OAI收割
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。