Cloning and phylogenetic analysis of an amphioxus myogenic bHLH gene AmphiMDF
文献类型：期刊论文
| 作者 | Yuan, JD; Zhang, SC; Liu, ZH; Luan, ZD; Hu, GX |
| 刊名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
 |
| 出版日期 | 2003 |
| 卷号 | 301期号:4页码:960-967 |
| 关键词 | amphioxus Branchiostoma belcheri tsingtauense archetype myogenic bHLH gene evolution phylogeny |
| 通讯作者 | Zhang, SC (reprint author), Ocean Univ Qingdao, Dept Marine Biol, Qingdao 266003, Peoples R China., |
| 英文摘要 | In this study, a member of the MyoD gene family, AmphiMDF, was isolated from the embryos of amphioxus by degenerate PCR, followed by rapid amplification of cDNA ends (RACE). Southern blot analysis confirmed that only a single myogenic bHLH gene was present in the genome of amphioxus Branchiostoma belcheri tsingtauense. Sequence and phylogenetic analyses indicated that AmphiMDF falls at the base of its vertebrate homologs. The amino acid sequence of AmphiMDF was almost equally similar to those of the four clusters of the vertebrate MyoD family. This suggests that AmphiMDF is not only the sister but also the archetype of the vertebrate myogenic bHLH genes. The scenarios to explain the origin of the vertebrate MyoD gene family from the ancestral myogenic bHLH gene like AmphiMDF are also discussed. (C) 2003 Elsevier Science (USA). All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | MUSCLE DIFFERENTIATION ; VERTEBRATE HEAD ; EXPRESSION ; EVOLUTION ; FAMILY ; MRF4 ; PROTEINS ; MEMBER ; MYF-5 ; EMBRYOGENESIS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000181362800023 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2288]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Yuan, JD,Zhang, SC,Liu, ZH,et al. Cloning and phylogenetic analysis of an amphioxus myogenic bHLH gene AmphiMDF[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2003,301(4):960-967. |
| APA | Yuan, JD,Zhang, SC,Liu, ZH,Luan, ZD,&Hu, GX.(2003).Cloning and phylogenetic analysis of an amphioxus myogenic bHLH gene AmphiMDF.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,301(4),960-967. |
| MLA | Yuan, JD,et al."Cloning and phylogenetic analysis of an amphioxus myogenic bHLH gene AmphiMDF".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 301.4(2003):960-967. |
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