The Xenopus noggin promoter drives roof-plate specific transcription
文献类型：期刊论文
| 作者 | Geng, X; Xiao, L; Tao, QH; Hu, RY; Rupp, RAW; Ding, XY |
| 刊名 | NEUROREPORT
 |
| 出版日期 | 2003 |
| 卷号 | 14期号:17页码:2163-2166 |
| 关键词 | neural patterning noggin REMI trangenesis roof plate Xenopus |
| 通讯作者 | Ding, XY (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Lab Stem Cell Biol,Lab Mol & Cell Biol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China.,xyding@sunm.shcnc.ac.cn |
| 英文摘要 | During vertebrate neural development, inductive signals derived from the roof plate specify dorsal neural cell types of spinal cord as well as adjacent dermomytotome. Noggin has been demonstrated to play a pivotal role in this signaling network but how its expression is regulated remains unclear. To investigate this issue, we identified a 2066 bp Xenopus noggin 5' flanking sequence which recapitulates the roof-plate expression of endogenous gene in transgenic frog tadpoles and we further mapped the roof-plate enhancer to a sequence as short as 79 bp. Our results, therefore, not only shed light on but also provide a powerful tool to the study of neural and somite patterning. |
| 学科主题 | Neurosciences & Neurology |
| 类目[WOS] | Neurosciences |
| 关键词[WOS] | EXPRESSION ; EMBRYOS ; ORGANIZER ; MESODERM ; CLONING ; BMP4 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000220208800006 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2379]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Geng, X,Xiao, L,Tao, QH,et al. The Xenopus noggin promoter drives roof-plate specific transcription[J]. NEUROREPORT,2003,14(17):2163-2166. |
| APA | Geng, X,Xiao, L,Tao, QH,Hu, RY,Rupp, RAW,&Ding, XY.(2003).The Xenopus noggin promoter drives roof-plate specific transcription.NEUROREPORT,14(17),2163-2166. |
| MLA | Geng, X,et al."The Xenopus noggin promoter drives roof-plate specific transcription".NEUROREPORT 14.17(2003):2163-2166. |
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