Ankyrin repeat mediated protein-protein interaction
文献类型：期刊论文
| 作者 | Du, HN; Hu, HY |
| 刊名 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
 |
| 出版日期 | 2002 |
| 卷号 | 29期号:1页码:42164 |
| 关键词 | ankyrin repeat ANK domain protein interaction disease |
| 通讯作者 | , |
| 英文摘要 | Ankyrin repeat (ANK) is a widely used sequence motif in organisms. An individual ankyrin repeat has an L-shaped structure consisting of a beta hairpin followed by two a helices, namely beta(2)alpha(2) pattern. These ANK repeats form a compact domain stabilized through hydrogen-bonding interaction and hydrophobic stacking. Massive of structurally similar but functionally diverse proteins containing ANK repeats can be formed by virtue of assembly of the tandem array motifs. The central role of ANK repeat is to mediate protein-protein interaction, so that proteins can make sophisticated functions by interacting with a variety of ligands. This review focuses on structure, function and related diseases of the ANK repeats and their complexes from several members of the ANK family. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 收录类别 | SCI |
| 语种 | 中文 |
| WOS记录号 | WOS:000174144100002 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2422]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Du, HN,Hu, HY. Ankyrin repeat mediated protein-protein interaction[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2002,29(1):42164. |
| APA | Du, HN,&Hu, HY.(2002).Ankyrin repeat mediated protein-protein interaction.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,29(1),42164. |
| MLA | Du, HN,et al."Ankyrin repeat mediated protein-protein interaction".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 29.1(2002):42164. |
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