中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis of Ser-His-Gly-DNA conjugates

文献类型:期刊论文

作者Li, XQ; Liu, H; Zhuang, M; Tan, B; Zhao, YF; Lu, CD
刊名ACTA BIOCHIMICA ET BIOPHYSICA SINICA
出版日期2002
卷号34期号:4页码:506-511
关键词oligonucleotide backbone peptide Ser-His-Gly phosphoramidite
通讯作者,
英文摘要There are strong interactions between the bases of oligonucleotides. Based on Watson-Crick principle, they can form stable secondary and tertiary structure such as hairpin, duplex, triplex, G-quartet, pseudoknot, which can serve as the scaffold of molecules. Peptides contain active groups such as amino, carboxyl, imidazole, hydroxyl. A protected Ser-His-Gly-Threoninol phosphoramidite was synthesized in this work and was incorporated into a triplex-forming oligonucleotide. The results indicate that the oligonucleotide containing Ser-His-Gly-Threoninol in the middle could still form triplex with the target duplex and the dissociation constant was 0.5 mumol/L.
学科主题Biochemistry & Molecular Biology; Biophysics
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]AMINO-ACIDS ; OLIGONUCLEOTIDES ; PEPTIDES ; HYBRIDS
收录类别SCI
语种中文
WOS记录号WOS:000177017300022
版本出版稿
源URL[http://202.127.25.143/handle/331003/2486]  
专题上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式
GB/T 7714
Li, XQ,Liu, H,Zhuang, M,et al. Synthesis of Ser-His-Gly-DNA conjugates[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2002,34(4):506-511.
APA Li, XQ,Liu, H,Zhuang, M,Tan, B,Zhao, YF,&Lu, CD.(2002).Synthesis of Ser-His-Gly-DNA conjugates.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,34(4),506-511.
MLA Li, XQ,et al."Synthesis of Ser-His-Gly-DNA conjugates".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 34.4(2002):506-511.

入库方式: OAI收割

来源:上海生物化学与细胞生物学研究所

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