C3G, a guanine nucleotide exchange factor bound to adapter molecule c-Crk, has two alternative splicing forms
文献类型：期刊论文
| 作者 | Zhai, B; Huo, HR; Liao, K |
| 刊名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
 |
| 出版日期 | 2001 |
| 卷号 | 286期号:1页码:61-66 |
| 关键词 | C3G alternative splicing adapter molecule guanine nucleotide exchange factor |
| 通讯作者 | Liao, K (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, State Lab Mol Biol, Inst Biochem & Cell Biol, 320 Yueyang Rd, Shanghai 200031, Peoples R China., |
| 英文摘要 | Two types of C3G cDNA were isolated from mouse 3T3-L1 adipocyte cDNA library. A 114-bp sequence in the middle of C3G cDNA is deleted in the short type cDNA. By RT-PCR analysis, it was found that these two types of C3G mRNA existed in all the mouse tissues. Sequence comparison revealed 88% nucleotide sequence identity between mouse and human C3G cDNA. Comparison of mouse C3G cDNA with the human genome database suggested that this 114-bp sequence comprised an entire exon, and it is confirmed by PCR analysis using mouse genomic DNA and cDNA template. These results indicate that two C3G mRNAs and proteins result from alternative RNA splicing. (C) 2001 Academic Press. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | DIFFERENTIATING 3T3-L1 PREADIPOCYTES ; ONCOGENE PRODUCT ; PROTEINS ; IDENTIFICATION ; EXPRESSION ; DOMAINS ; KINASE ; RAP1 ; GRB2 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000170519100010 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2574]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Zhai, B,Huo, HR,Liao, K. C3G, a guanine nucleotide exchange factor bound to adapter molecule c-Crk, has two alternative splicing forms[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2001,286(1):61-66. |
| APA | Zhai, B,Huo, HR,&Liao, K.(2001).C3G, a guanine nucleotide exchange factor bound to adapter molecule c-Crk, has two alternative splicing forms.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,286(1),61-66. |
| MLA | Zhai, B,et al."C3G, a guanine nucleotide exchange factor bound to adapter molecule c-Crk, has two alternative splicing forms".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286.1(2001):61-66. |
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