GABA transporter 1 transcriptional starting site exhibiting tissue specific difference
文献类型：期刊论文
| 作者 | Jin, XP; Huang, F; Yang, N; Lu, BF; Fei, J; Guo, LH |
| 刊名 | CELL RESEARCH
 |
| 出版日期 | 2001 |
| 卷号 | 11期号:2页码:161-163 |
| 关键词 | GABA transporter 1(GAT1) transcriptional starting site 5 ' RACE tissue specific difference DNA sequencing |
| 通讯作者 | Fei, J (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, 320 Yueyang Rd, Shanghai 200031, Peoples R China., |
| 英文摘要 | GABA transporter 1(GAT1) takes important roles in multiple physiological processes through the uptake and release of GABA, but the regulation of GAT1 gene expression in different tissues is rarely known. To address the question, first, 5' Rapid amplification of cDNA end (RACE) was used to determine GAT1 transcriptional starting sites in neonatal mouse cerebral cortex and intestine, adult mouse brain and adult rat testis. The products of 5'RACE were confirmed by DNA sequencing. We found that the transcript of GAT1 in neonatal mouse cerebral cortex and adult mouse brain starts at the same site (inside of exon 1), while in mouse intestine, GAT1 starts transcription in intron 1, and in rat testis, the transcript of GAT1 has an additional untranslation exon to the 5' direction. |
| 学科主题 | Cell Biology |
| 类目[WOS] | Cell Biology |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000169787000012 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2601]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Jin, XP,Huang, F,Yang, N,et al. GABA transporter 1 transcriptional starting site exhibiting tissue specific difference[J]. CELL RESEARCH,2001,11(2):161-163. |
| APA | Jin, XP,Huang, F,Yang, N,Lu, BF,Fei, J,&Guo, LH.(2001).GABA transporter 1 transcriptional starting site exhibiting tissue specific difference.CELL RESEARCH,11(2),161-163. |
| MLA | Jin, XP,et al."GABA transporter 1 transcriptional starting site exhibiting tissue specific difference".CELL RESEARCH 11.2(2001):161-163. |
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