Spatial learning and morphine-rewarded place preference negatively correlates in mice
文献类型：期刊论文
| 作者 | Xu, NJ; Wang, LZ; Wu, CF; Pei, G |
| 刊名 | PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
 |
| 出版日期 | 2001 |
| 卷号 | 68期号:3页码:389-394 |
| 关键词 | morphine conditioned place preference Morris water maze Y-maze spontaneous alternation task |
| 通讯作者 | Pei, G (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Biochem & Cell Biol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China., |
| 英文摘要 | Accumulating evidence has indicated that there might exist some correlation between opiate reward and certain kinds of learning and memory processes. The present study attempted to investigate the correlation between individual differences in morphine reward and capacities in spatial learning and spontaneous alternation. In the present studies, good-response (GR) and poor-response (PR) mice were respectively selected according to their performance in a spatial learning test involving the Morris water maze or in a spontaneous alternation task using the Y-maze. In a place preference conditioning procedure, morphine (3.0 mg/kg) produced significant conditioned place preference (CPP) in both GR and PR mice selected by using either the Morris water maze or the Y-maze. The PR mice selected with the Morris water maze showed significantly mon CPP induced by morphine than the GR mice. However, no detectable difference was observed in morphine-induced CPP between the GR and PR mice selected with the Y-maze. These results suggested that the variation in morphine-induced CPP in mice is somehow differentially related to that of spatial learning but unlikely to that of spontaneous alternation. (C) 2001 Elsevier Science Inc. All rights reserved. |
| 学科主题 | Behavioral Sciences; Neurosciences & Neurology; Pharmacology & Pharmacy |
| 类目[WOS] | Behavioral Sciences ; Neurosciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | PROTEIN-KINASE-II ; ELEMENT-BINDING PROTEIN ; OPIOID RECEPTOR ; SPONTANEOUS-ALTERNATION ; INDIVIDUAL-DIFFERENCES ; RAT HIPPOCAMPUS ; TRANSGENIC MICE ; MEMORY ; NMDA ; ATTENUATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000168312400004 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2634]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Xu, NJ,Wang, LZ,Wu, CF,et al. Spatial learning and morphine-rewarded place preference negatively correlates in mice[J]. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR,2001,68(3):389-394. |
| APA | Xu, NJ,Wang, LZ,Wu, CF,&Pei, G.(2001).Spatial learning and morphine-rewarded place preference negatively correlates in mice.PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR,68(3),389-394. |
| MLA | Xu, NJ,et al."Spatial learning and morphine-rewarded place preference negatively correlates in mice".PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 68.3(2001):389-394. |
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