New frontiers in the proteome research: Quantitative proteomics
文献类型：期刊论文
| 作者 | Yuan, Q; Zhao, FK |
| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
 |
| 出版日期 | 2001 |
| 卷号 | 33期号:5页码:477-482 |
| 关键词 | quantitative proteomics two-dimensional gel electrophoresis molecular scanner isotope-coded affinity tags (ICAT) protein chip |
| 通讯作者 | , |
| 英文摘要 | In the past years, proteome research has achieved very exciting advances. The automation of 2DEMS approach and the use of multidimensional liquid chromatography (LC) and tandem mass spectrometry (MS/MS) have overcome many disadvantages of two-dimensional gel electrophoresis. The stable isotope labeling and the isotope-coded affinity tags (ICAT) strategy provided an ideal method for accurately quantitating the low copy number proteins which play a key role in cells or tissues. At the same time, the research of the quantitative proteomics has been improved greatly with the development of the protein chip technology. Recent advances of the research in the quantitative proteomics and the related technologies are reviewed. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | MOLECULAR SCANNER ; MASS-SPECTROMETRY ; PROTEINS ; ANTIBODIES ; EXPRESSION |
| 收录类别 | SCI |
| 语种 | 中文 |
| WOS记录号 | WOS:000171403600002 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2665]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Yuan, Q,Zhao, FK. New frontiers in the proteome research: Quantitative proteomics[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2001,33(5):477-482. |
| APA | Yuan, Q,&Zhao, FK.(2001).New frontiers in the proteome research: Quantitative proteomics.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,33(5),477-482. |
| MLA | Yuan, Q,et al."New frontiers in the proteome research: Quantitative proteomics".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 33.5(2001):477-482. |
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