Homology modeling of Bacillus subtilis tryptophanyl-tRNA synthetase
文献类型：期刊论文
| 作者 | Chen, L; Jiang, G; Jin, YX; Wang, DB |
| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
 |
| 出版日期 | 2001 |
| 卷号 | 33期号:6页码:687-690 |
| 关键词 | tryptophanyl-tRNA synthetase homology modeling energy optimization identity amino acid |
| 通讯作者 | , |
| 英文摘要 | Tryptophanyl-tRNA synthetase (TrpRS) plays a pivotal role in protein synthesis. However, till now no stereostructural data of Bacillus subtilis TrpRS were reported. Here, by using the homology modeling using Bacillus stearothermophilus TrpRS as a template, it is demonstrated that the synthetase has 16 alpha helices and 5 beta sheets. The only tryptophan Trp(92) is located on the interface of subunits. Also the modeling presents the ligand binding site, active site and the putative binding of tRNA(Trp). |
| 学科主题 | Biochemistry & Molecular Biology ; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | TRANSFER-RNA-SYNTHETASE ; NUCLEOTIDE-SEQUENCE ; ESCHERICHIA-COLI ; STRUCTURAL GENE |
| 收录类别 | SCI |
| 语种 | 中文 |
| WOS记录号 | WOS:000172362600016 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2690]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Chen, L,Jiang, G,Jin, YX,et al. Homology modeling of Bacillus subtilis tryptophanyl-tRNA synthetase[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2001,33(6):687-690. |
| APA | Chen, L,Jiang, G,Jin, YX,&Wang, DB.(2001).Homology modeling of Bacillus subtilis tryptophanyl-tRNA synthetase.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,33(6),687-690. |
| MLA | Chen, L,et al."Homology modeling of Bacillus subtilis tryptophanyl-tRNA synthetase".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 33.6(2001):687-690. |
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