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Transgenic mice overexpressing gamma-aminobutyric acid transporter subtype I develop obesity
文献类型：期刊论文
| 作者 | Ma, YH; Hu, JH; Zhou, XG; Zeng, RW; Mei, ZT; Fei, J; Guo, LH |
| 刊名 | CELL RESEARCH
 |
| 出版日期 | 2000 |
| 卷号 | 10期号:4页码:303-310 |
| 关键词 | gamma-aminobutyric acid transporter subtype I transgenic mouse obesity |
| 通讯作者 | Fei, J (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Shanghai 200031, Peoples R China., |
| 英文摘要 | Transgenic mice ubiquitously overexpressing murine gamma -aminobutyric acid transporter subtype I were created. Unexpectedly, these mice markedly exhibited heritable obesity, which features significantly increased body weight and fat deposition. Behavioral examination revealed that transgenic mice have slightly reduced spontaneous locomotive capacity and altered feeding pattern. This preliminary finding indicates that the inappropriate level of gamma -aminobutyric acid transporters may be directly or indirectly involved in the pathogenic mechanism underlying certain types of obesity. |
| 学科主题 | Cell Biology |
| 类目[WOS] | Cell Biology |
| 关键词[WOS] | NEUROTRANSMITTER TRANSPORTERS ; GABA TRANSPORTER ; PITUITARY-GLAND ; LOCALIZATION ; BRAIN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000166201200005 |
| 版本 | 出版稿 |
| 源URL | [http://202.127.25.143/handle/331003/2741]  |
| 专题 | 上海生化细胞研究所_上海生科院生化细胞研究所 |
| 推荐引用方式 GB/T 7714 | Ma, YH,Hu, JH,Zhou, XG,et al. Transgenic mice overexpressing gamma-aminobutyric acid transporter subtype I develop obesity[J]. CELL RESEARCH,2000,10(4):303-310. |
| APA | Ma, YH.,Hu, JH.,Zhou, XG.,Zeng, RW.,Mei, ZT.,...&Guo, LH.(2000).Transgenic mice overexpressing gamma-aminobutyric acid transporter subtype I develop obesity.CELL RESEARCH,10(4),303-310. |
| MLA | Ma, YH,et al."Transgenic mice overexpressing gamma-aminobutyric acid transporter subtype I develop obesity".CELL RESEARCH 10.4(2000):303-310. |
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