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Multilocus association mapping using generalized ridge logistic regression

文献类型：期刊论文

作者Liu, Zhe2; Shen, Yuanyuan3; Ott, Jurg1
刊名BMC BIOINFORMATICS
出版日期2011-09-29
卷号12
ISSN号1471-2105
通讯作者Ott, J (reprint author), Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, 4A Datun Rd, Beijing 100101, Peoples R China.
产权排序3
英文摘要Background: In genome-wide association studies, it is widely accepted that multilocus methods are more powerful than testing single-nucleotide polymorphisms (SNPs) one at a time. Among statistical approaches considering many predictors simultaneously, scan statistics are an effective tool for detecting susceptibility genomic regions and mapping disease genes. In this study, inspired by the idea of scan statistics, we propose a novel sliding window-based method for identifying a parsimonious subset of contiguous SNPs that best predict disease status.
学科主题Physiological psychology/Biological Psychology
收录类别SCI
项目简介This work has been supported by NSFC grants from the Chinese government (project numbers 30730057 and 30700442) to JO.
原文出处http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224109/pdf/1471-2105-12-384.pdf
语种英语
WOS记录号WOS:000295848700001
源URL[http://ir.psych.ac.cn/handle/311026/12862]  
专题心理研究所_中国科学院心理健康重点实验室
作者单位1.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China
2.Univ Chicago, Dept Stat, Chicago, IL 60637 USA
3.Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
推荐引用方式
GB/T 7714		 Liu, Zhe,Shen, Yuanyuan,Ott, Jurg. Multilocus association mapping using generalized ridge logistic regression[J]. BMC BIOINFORMATICS,2011,12.
APA Liu, Zhe,Shen, Yuanyuan,&Ott, Jurg.(2011).Multilocus association mapping using generalized ridge logistic regression.BMC BIOINFORMATICS,12.
MLA Liu, Zhe,et al."Multilocus association mapping using generalized ridge logistic regression".BMC BIOINFORMATICS 12(2011).

入库方式： OAI收割

来源：心理研究所

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